Epidemiology of bronchopulmonary dysplasia

被引:124
作者
Van Marter, Linda J. [1 ,2 ]
机构
[1] Childrens Hosp, Boston, MA 02115 USA
[2] Harvard Univ, Brigham & Womens Hosp, Sch Med, Boston, MA 02115 USA
关键词
Bronchopulmonary dysplasia; Caffeine; Continuous positive airway pressure; Epidemiology; Inhaled nitric oxide; Non-invasive ventilation; INHALED NITRIC-OXIDE; CHRONIC LUNG-DISEASE; BIRTH-WEIGHT INFANTS; POSITIVE AIRWAY PRESSURE; RANDOMIZED CONTROLLED-TRIAL; VITAMIN-A SUPPLEMENTATION; RESPIRATORY-DISTRESS-SYNDROME; BRONCHOALVEOLAR LAVAGE FLUID; PREMATURE-INFANTS; PRETERM INFANTS;
D O I
10.1016/j.siny.2009.08.007
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
First described more than 40 years ago, bronchopulmonary dysplasia (BPD) remains one of the most serious and vexing challenges in the care of very preterm infants. Affecting approximately one-quarter of infants born <1500 g birth weight, BPD is associated with prolonged neonatal intensive care unit hospitalization, greater risk of neonatal and post-neonatal mortality and a host of associated medical and neurodevelopmental sequelae. This seminar focuses on the epidemiology and definition of BPD as well as the current evidence pertaining to a number of potential preventive treatments for BPD: non-invasive respiratory support technologies, inhaled nitric oxide, vitamin A, and caffeine. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:358 / 366
页数:9
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