Microbiology of Pediatric Orbital Cellulitis and Trends in Methicillin-Resistant Staphylococcus aureus Cases

被引:16
作者
Hsu, Jerry [1 ,2 ]
Treister, Alison D. [1 ,2 ]
Ranaivo, Hantamalala Ralay [2 ]
Rowley, Anne H. [1 ,2 ]
Rahmani, Bahram [1 ,2 ]
机构
[1] Northwestern Univ, Chicago, IL 60611 USA
[2] Ann & Robert H Lurie Childrens Hosp Chicago, Chicago, IL 60611 USA
关键词
orbital cellulitis; pediatric; microbiology; methicillin-resistant Staphylococcus aureus; antibiotics;
D O I
10.1177/0009922819864587
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
We reviewed medical records of children with orbital cellulitis with positive cultures at a tertiary institution from 2005 to 2018 to identify microbiology trends and features associated with methicillin-resistant Staphylococcus aureus (MRSA) cases. Cultures obtained from the orbits (n = 33), sinuses (n = 31), and dural cavities (n = 4) had yields of 66.7%, 61.3%, and 75%, respectively, compared with 17.6% of blood cultures (n = 69). Fifty-five patients had positive culture results. Staphylococcus aureus was the most common pathogen isolated (n = 19), followed by Streptococcus species, most commonly Streptococcus anginosus (n = 8). The most frequently prescribed antibiotic combination regimen was ampicillin-sulbactam followed by amoxicillin-clavulanate. There were 8 cases of MRSA. MRSA was associated with an age of presentation <1 year old (P = .034). Other clinical features were similar between MRSA and non-MRSA cases. In infants and neonates, or those with epidemiologic risk factors, MRSA should also be considered.
引用
收藏
页码:1056 / 1062
页数:7
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