Mediastinal Mucormycosis: Case report, review of literature and treatment with continuous liposomal amphotericin B irrigation

被引：6

作者：

Cooper, Joseph D. ^{[1
,2
]}

Gotoff, Robert A. ^{[3
]}

Foltzer, Michael A. ^{[4
]}

Carter, Russell A. ^{[5
]}

Walsh, Thomas J. ^{[6
,7
,8
]}

机构：

[1] Montefiore Med Ctr, Dept Med, Div Infect Dis, The Bronx, NY USA

[2] Albert Einstein Coll Med, The Bronx, NY USA

[3] Geisinger Med Ctr, Dept Med, Div Hosp Med, Danville, PA 17822 USA

[4] Geisinger Med Ctr, Dept Med, Div Infect Dis, Danville, PA 17822 USA

[5] Geisinger Med Ctr, Dept Surg, Div Cardiac Surg, Danville, PA 17822 USA

[6] Cornell Univ, Weill Cornell Med Ctr, Transplantat Oncol Infect Dis Program, Dept Med, New York, NY 10021 USA

[7] Cornell Univ, Weill Cornell Med Ctr, Transplantat Oncol Infect Dis Program, Dept Pediat, New York, NY 10021 USA

[8] Cornell Univ, Weill Cornell Med Ctr, Transplantat Oncol Infect Dis Program, Dept Microbiol & Immunol, New York, NY 10021 USA

来源：

MYCOSES | 2019年 / 62卷 / 09期

关键词：

liposomal amphotericin B irrigation; mediastinal mucormycosis; SALVAGE THERAPY; ZYGOMYCOSIS;

D O I：

10.1111/myc.12922

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Mediastinal mucormycosis is an uncommon but lethal infection associated with an 83% mortality. We describe a case of fatal Rhizopus microsporus mediastinitis despite three exploratory mediastinal surgeries and complementary systemic and mediastinal irrigation with liposomal amphotericin B. We further review the literature on surgical and antifungal management of mediastinal mucormycosis.

引用

页码：739 / 745

页数：7

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