Expanding Role of Donation After Circulatory Death Donors in Liver Transplantation

被引:7
作者
Croome, Kristopher P. [1 ]
Taner, C. Burcin [1 ]
机构
[1] Mayo Clin Florida, Dept Transplant, 4500 San Pablo Rd, Jacksonville, FL 32224 USA
关键词
DCD; HCC; Non-heart beating; Ischemic cholangiopathy; Allocation; EARLY ALLOGRAFT DYSFUNCTION; LONG-TERM OUTCOMES; CARDIAC-DEATH; ISCHEMIC CHOLANGIOPATHY; BILIARY COMPLICATIONS; FAILED DONATION; SINGLE-CENTER; GRAFTS; RECIPIENTS; SURVIVAL;
D O I
10.1016/j.cld.2020.08.005
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Better understanding of how to utilize donation after circulatory death (DCD) liver grafts has resulted in improved national outcomes and expansion in the number of DCD liver transplants (LTs). This improvement has been driven by better donor and recipient matching, careful evaluation of hemodynamics during withdrawal of life support, and refinement of the procurement operation. Changes to liver allocation likely will result in increased utilization of DCD liver grafts. Ischemic cholangiopathy remains the Achilles heel of DCD LTs and, although rates have fallen with improved protocols, a certain rate likely is unavoidable. This review discusses contemporary issues with DCD LTs. © 2020 Elsevier Inc.
引用
收藏
页码:73 / 88
页数:16
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