Inhibition by serum antioxidants of luminol oxidation in the presence of hemoglobin and hydrogen peroxide

被引:0
|
作者
Teselkin, YO [1 ]
Babenkova, IV [1 ]
Lyubitsky, OB [1 ]
Klebanov, GI [1 ]
Vladimirov, YA [1 ]
机构
[1] RUSSIAN STATE MED UNIV,DEPT BIOPHYS,MOSCOW 117869,RUSSIA
来源
VOPROSY MEDITSINSKOI KHIMII | 1997年 / 43卷 / 02期
关键词
hemoglobin; hydrogen peroxide; luminol free radical oxidation; chemiluminescence; serum antioxidants;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The effect of human blood serum and several serum antioxidants (ascorbate, a-tocopherol, urate, albumin, transferrin and ceruloplasmin) on latent period and chemiluminescence (CL) intencity of hemoglobin-hydrogen peroxide-luminol system has been investigated. The addition of blood serum and antioxidants to the system increased the latent period and decreased CL intencity. The antioxidants had been taken in concentrations caused 50% inhibition of CL intencity of model system had not effected on the luminol photoluminescence. The possible mechanism of action of the antioxidants is discussed.
引用
收藏
页码:87 / 93
页数:7
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