Toxic effects of nanoparticles on bioluminescence activity, seed germination, and gene mutation

被引:38
作者
Ko, Kyung-Seok [1 ]
Kong, In Chul [2 ]
机构
[1] KIGAM, Geol Environm Div, Taejon, South Korea
[2] Yeungnam Univ, Dept Environm Engn, Gyungsan Si 712749, Kyungbuk, South Korea
基金
新加坡国家研究基金会;
关键词
Bioassays; Bioluminescence; Mutation; Nanoparticle (NP); Seed germination; ENGINEERED NANOPARTICLES; CONTAMINATED SOILS; ROOT ELONGATION; ECOTOXICITY; GROWTH; PLANTS; TIO2; PHYTOTOXICITY; NANOMATERIALS; TESTS;
D O I
10.1007/s00253-013-5404-x
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The potential environmental toxicities of several metal oxide nanoparticles (NPs; CuO, TiO2, NiO, Fe2O3, ZnO, and Co3O4) were evaluated in the context of bioluminescence activity, seed germination, and bacterial gene mutation. The bioassays exhibited different sensitivities, i.e., each kind of NP exhibited a different level of toxicity in each of the bioassays. However, with a few exceptions, CuO and ZnO NPs had most toxic for germination of Lactuca seed (EC50 0.46 mg CuO/l) and bioluminescence (EC50 1.05 mg ZnO/l). Three NPs (Co3O4, TiO2, and Fe2O3) among all tested concentrations (max. 1,000 mg/l) showed no inhibitory effects on the tested organisms, except for Co3O4 NPs on bioluminescence activity (EC50 62.04 mg/l). The sensitivity of Lactuca seeds was greater than that of Raphanus seeds (EC50 0.46 mg CuO/l versus 26.84 mg CuO /l ). The ranking of metal toxicity levels on bioluminescence was in the order of ZnO > CuO > Co3O4 > NiO > Fe2O3, TiO2, while CuO > ZnO > NiO > Co3O4, Fe2O3, TiO2 on germination. No revertant mutagenic ratio (greater than 2.0) of Salmonella typhimurium TA 98 was observed under any tested condition. These findings demonstrate that several bioassays, as opposed to any single one, are needed for the accurate assessment of NP toxicity on ecosystems.
引用
收藏
页码:3295 / 3303
页数:9
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