The origin of embryonic and fetal myoblasts: a role of Pax3 and Pax7

被引：53
|
作者：
Messina, Graziella
Cossu, Giulio [1 ]
机构：
[1] Ist Sci San Raffaele, Div Regenerat Med, I-20132 Milan, Italy
来源：
GENES & DEVELOPMENT | 2009年 / 23卷 / 08期
关键词：
Pax3; Pax7; beta-catenin; limb; myogenesis; MUSCLE PROGENITOR CELLS; SKELETAL MYOGENESIS; EXPRESSION ANALYSIS; MYF5; EXPRESSION; SATELLITE CELLS; SOMITIC ORIGIN; MESODERM; POPULATION; MOUSE; MYOD;
D O I：
10.1101/gad.1797009
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Skeletal muscle is a heterogeneous tissue composed of individual muscle fibers, diversified in size, shape, and contractile protein content, to fulfill the different functional needs of the vertebrate body. This heterogeneity derives from and depends at least in part on distinct classes of myogenic progenitors; i.e., embryonic and fetal myoblasts and satellite cells whose origin and lineage relationship have been elusive so far. In this issue of Genes & Development, Hutcheson and colleagues (pp. 997-1013) provide a first answer to this question.
引用
收藏
页码：902 / 905
页数：4
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