Evaluation of the knowledge of intermittent preventive treatment during pregnancy (IPTp) with sulfadoxine-pyrimethamine in Ivory Coast

In 2006, because of the chloroquine-resistance and following the World Health Organization (WHO) recommendations, Cote d'Ivoire adopted a new policy for the prevention of malaria during pregnancy by intermittent preventive treatment in pregnancy with sulfadoxine pyrimethamine (IPTp-SP). However, its implementation remains limited. Objectives of this study were to evaluate the knowledge of the TPIp-SP regimen and prescribers opinion concerning this protocol. It was a knowledge attitude and pratices (KAP) cross-sectional descriptive study. We used a two-stage stratified sounding. The study took place in 12 health facilities in the health region of Abidjan 2 from march to august 2016 and involved 187 health professionals. We performed descriptive analysis, univariate and bivariate comparative analysis. The study found that half of the prescribers surveyed actually knew the ITPp program (SP - 3 doses - 2nd and 3rd trimesters). Knowledge was better among practitioners with more than 5 years of exercise (P = 0.011) and at the level of first contact of health institution (P = 0.001). Half of the prescribers were in favor of applying the protocol. The level of knowledge of prescribers has changed little in 2016 compared to 2008 for physicians (Pr (vertical bar Z vertical bar < vertical bar z vertical bar) = 0.4861) or midwives Pr (vertical bar Z vertical bar < vertical bar z vertical bar) = 0.4786). Prescribers remained faithful to the old 2-dose protocol. The opinion on the protocol was better in 2016 compared to 2008 Pr (Z < z) = 0.0052. Effective knowledge of the ITPp regimen remains average for many years after its implementation. However opinions are better. Strengthening prevention interventions with health professionals is necessary for effective implementation of this protocol. (C) 2019 Societe francaise de pharmacologie et de therapeutique. Published by Elsevier Masson SAS.