Use of cyclotrons in medicine

被引：41

作者：

Qaim, SM ^{[1
]}

机构：

[1] Forschungszentrum Julich, Inst Nukl Chem, D-52425 Julich, Germany

来源：

RADIATION PHYSICS AND CHEMISTRY | 2004年 / 71卷 / 3-4期

关键词：

cyclotron; radionuclide; emission tomography; hadron and internal radiotherapy;

D O I：

10.1016/j.radphyschem.2004.04.124

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Cyclotrons are versatile ion-accelerating machines which find many applications in medicine. In this short review their use in hadron therapy is briefly discussed. Proton therapy is gaining significance because of its capability to treat deep-lying tumours. A strong area of application of cyclotrons involves the production of short-lived neutron deficient radiotracers for use in emission tomography, especially positron emission tomography. This fast and quantitative in vivo diagnostic technique is being increasingly used in neurology, cardiology and oncology. Besides routine patient care, considerable interdisciplinary work on development of new positron emitters is under way. A short account of those efforts is given. The use of cyclotrons in the production of radionuclides for internal radiotherapy is also briefly described. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：917 / 926

页数：10

共 22 条

[1] PET quantitation and imaging of the non-pure positronemitting iodine isotope 124I [J].

Herzog, H ;

Tellmann, L ;

Qaim, SM ;

Spellerberg, S ;

Schmid, A ;

Coenen, HH .

APPLIED RADIATION AND ISOTOPES, 2002, 56 (05) :673-679

[2]

HERZOG H, 1993, J NUCL MED, V34, P2222

[3]

Hess E, 2001, RADIOCHIM ACTA, V89, P357, DOI 10.1524/ract.2001.89.6.357

[4] Excitation functions of 125Te(p, xn)-reactions from their respective thresholds up to 100 MeV with special reference to the production of 124I [J].

Hohn, A ;

Nortier, FM ;

Scholten, B ;

van der Walt, TN ;

Coenen, HH ;

Qaim, SM .

APPLIED RADIATION AND ISOTOPES, 2001, 55 (02) :149-156

[5] Overview of hadron therapy: rationales, present status and future prospects [J].

Jones, DTL .

RADIOCHIMICA ACTA, 2001, 89 (4-5) :235-244

[6]

Kraft G, 1997, INT CONGR SER, V1144, P38

[7] PRODUCTION OF I-124 [J].

LAMBRECHT, RM ;

SAJJAD, M ;

QURESHI, MA ;

ALYANBAWI, SJ .

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-LETTERS, 1988, 127 (02) :143-150

[8]

Prieels D, 2001, AIP CONF PROC, V576, P857, DOI 10.1063/1.1395438

[9]

Qaim S. M., 2002, Journal of Nuclear Science and Technology, V2, P1272

[10]

Qaim SM, 2003, HANDBOOK OF NUCLEAR CHEMISTRY, VOL 4, P47

← 1 2 3 →