G protein-coupled receptor kinase-2 phosphorylates and selectively desensitizes receptor tyrosine kinases

被引:0
|
作者
Kim, L [1 ]
Murray, JP [1 ]
Exum, ST [1 ]
Peppel, K [1 ]
Freedman, NJ [1 ]
机构
[1] Duke Univ, Med Ctr, Durham, NC USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1005
引用
收藏
页码:200 / 200
页数:1
相关论文
共 50 条
  • [1] The platelet-derived growth factor receptor β-tyrosine phosphorylates G protein-coupled receptor kinase-2:: Mechanism for feedback inhibition
    Wu, JH
    Kim, LK
    Peppel, K
    Freedman, NJ
    CIRCULATION, 2004, 110 (17) : 186 - 186
  • [2] PDGF receptor desensitization by G protein-coupled receptor kinase-2
    Murray, JP
    Peppel, K
    Freedman, NJ
    CIRCULATION, 2000, 102 (18) : 274 - 274
  • [3] The platelet-derived growth factor receptor-β phosphorylates and activates g protein-coupled receptor kinase-2
    Wu, JH
    Goswami, R
    Kim, LK
    Miller, WE
    Peppel, K
    Freedman, NJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (35) : 31027 - 31035
  • [4] PDGF receptor phosphorylation and desensitization by G protein-coupled receptor kinase-2
    Parvani, JG
    Brian, L
    Murray, JP
    Peppel, K
    Freedman, NJ
    CIRCULATION, 2001, 104 (17) : 62 - 62
  • [5] Opioid receptor types selectively cointernalize with G protein-coupled receptor kinases 2 and 3
    Schulz, R
    Wehmeyer, A
    Schulz, K
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 300 (02): : 376 - 384
  • [6] G protein-coupled receptor kinases
    Pitcher, JA
    Freedman, NJ
    Lefkowitz, RJ
    ANNUAL REVIEW OF BIOCHEMISTRY, 1998, 67 : 653 - 692
  • [7] The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin
    Pitcher, JA
    Hall, RA
    Daaka, Y
    Zhang, J
    Ferguson, SSG
    Hester, S
    Miller, S
    Caron, MG
    Lefkowitz, RJ
    Barak, LS
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (20) : 12316 - 12324
  • [8] Integrin regulation of receptor tyrosine kinase and G protein-coupled receptor signaling to mitogen-activated protein kinases
    Juliano, RL
    Aplin, AE
    Howe, AK
    Short, S
    Lee, JW
    Alahari, S
    REGULATORS AND EFFECTORS OF SMALL GTPASES, PT G: RAS FAMILY II, 2001, 333 : 151 - 163
  • [9] Dissecting how receptor tyrosine kinases modulate G protein-coupled receptor function
    Adolfo Garcia-Sainz, J.
    Teresa Romero-Avila, M.
    del Carmen Medina, Luz
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2010, 648 (1-3) : 1 - 5
  • [10] Receptor tyrosine kinases are signaling intermediates of G protein-coupled receptors
    Piiper, A
    Zeuzem, S
    CURRENT PHARMACEUTICAL DESIGN, 2004, 10 (28) : 3539 - 3545