Studies toward the total synthesis of cyclodidemniserinol trisulfate. Part II: 3,5,7-Trisubstituted 6,8-dioxabicyclo [3.2.1] octane core structure construction via I2-mediated deprotection and ring closure tandem reaction

被引：12

作者：

Liu, Jian-Hua ^{[1
]}

Long, Ya-Qiu ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 32期

基金：

中国国家自然科学基金;

关键词：

ESTERS;

D O I：

10.1016/j.tetlet.2009.05.088

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 3,5,7-trisubstituted 6.8-dioxabicyclo [3.2.1] octane core structure was synthesized by employing a chiral pool convergent synthesis strategy and the I-2-mediated simultaneous deprotection and ring closure reaction as the key step, providing a practical and efficient synthetic approach applicable to the further total synthesis of the natural product cyclodidemniserinol trisulfate. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：4592 / 4594

页数：3

共 2 条

[1] Studies toward the total synthesis of cyclodidemniserinol trisulfate. Part I: 3,5,7-Trisubstituted 6,8-dioxabicyclo [3.2.1] octane core structure construction via a convergent and a linear stereoselective synthesis
Liu, Jian-Hua
Song, Lai-Dong
Long, Ya-Qiu
TETRAHEDRON LETTERS, 2009, 50 (32) : 4587 - 4591
[2] Synthesis of the C5-C30 fragment of cyclodidemniserinol trisulfate via I2-mediated deprotection and ring closure tandem reaction
Liu, Jian-Hua
Jin, Yi
Long, Ya-Qiu
TETRAHEDRON, 2010, 66 (06) : 1267 - 1273

← 1 →