Synthesis of 5-Methyl-1,2,4-triazolo[1,5-a]Pyrimidin-7(4H)-one - a Semi-Product of the Synthesis of Antiviral Drug Triazide® in the Conditions of Microwave Excitation

被引：1

作者：

Baklykov, Artem, V ^{[1
,2
]}

Rusinov, Gennady L. ^{[1
,2
]}

Artem'ev, Grigory A. ^{[1
]}

Kopchuk, Dmitry S. ^{[1
,2
]}

Zyryanov, Grigory, V ^{[1
,2
]}

Rusinov, Vladimir L. ^{[1
,2
]}

Charushin, Valery N. ^{[1
,2
]}

机构：

[1] RAS, I Ya Postovsky Inst Organ Synth, Ural Div, 22-20 S Kovalevskoy Akad Skaya St, Ekaterinburg 62099, Russia

[2] Ural Fed Univ, 19 Mira St, Ekaterinburg 62000, Russia

来源：

PROCEEDINGS OF THE II INTERNATIONAL CONFERENCE: MODERN SYNTHETIC METHODOLOGIES FOR CREATING DRUGS AND FUNCTIONAL MATERIALS (MOSM2018) | 2019年 / 2063卷

基金：

俄罗斯科学基金会;

关键词：

D O I：

10.1063/1.5087337

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

5-Methyl-1,2,4-triazolo[1,5-a]pyrimidine-7(4H)-one was synthesized (the intermediate product for the synthesis of the antiviral drug Triazide (R)) under microwave radiation. Conversion of the starting reagents to the target product reached 95% due to experimentally selected conditions.

引用

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