Identification of a fragmented small GTPase capable of conditional effector binding

被引：0
|
作者：
Zhao, Jia [1 ]
Stains, Cliff I. [1 ]
机构：
[1] Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA
来源：
RSC ADVANCES | 2017年 / 7卷 / 20期
关键词：
GREEN FLUORESCENT PROTEIN; LIVING CELLS; RHO GTPASES; SIGNAL-TRANSDUCTION; MINIPROTEIN HOST; RAS; DOMAIN; CDC42; DIMERIZATION; SWITCH;
D O I：
10.1039/c6ra25575b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A fragmented small GTPase capable of conditional effector binding is described. The effector binding function of this split-GTPase can be modulated using a small molecule input, thus allowing for the potential design of cellular signaling pathways.
引用
收藏
页码：12265 / 12268
页数：4
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