Three-component coupling reactions in ionic liquids: An improved protocol for the synthesis of 1,4-dihydropyridines

被引：79

作者：

Yadav, JS ^{[1
]}

Reddy, BVS ^{[1
]}

Basak, AK ^{[1
]}

Narsaiah, AV ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

GREEN CHEMISTRY | 2003年 / 5卷 / 01期

关键词：

D O I：

10.1039/b210017g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three-component condensation of aldehyde, beta-ketoester and methyl 3-aminocrotonate proceeds smoothly in 1-n-butyl-3-methylimidazolium tetrafluoroborate [bmim]BF4 or 1-n-butyl-3-methylimidazolium hexafluorophosphate [bmim]PF6 ionic liquids at room temperature under mild conditions to afford the corresponding 1,4-dihydropyridine derivatives in high yields. The recovered activated ionic liquids are recycled for four to five runs with no loss in activity.

引用

页码：60 / 63

页数：4

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