A fast algorithm for estimating transmission probabilities in QTL detection designs with dense maps

被引：2

作者：

Elsen, Jean-Michel ^{[1
]}

Filangi, Olivier ^{[2
]}

Gilbert, Helene ^{[3
]}

Le Roy, Pascale ^{[2
]}

Moreno, Carole ^{[1
]}

机构：

[1] INRA, SAGA, F-31326 Castanet Tolosan, France

[2] INRA, GARen, F-35000 Rennes, France

[3] INRA, GABI, F-78352 Jouy En Josas, France

来源：

GENETICS SELECTION EVOLUTION | 2009年 / 41卷

关键词：

QUANTITATIVE TRAIT LOCI;

D O I：

10.1186/1297-9686-41-50

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Background: In the case of an autosomal locus, four transmission events from the parents to progeny are possible, specified by the grand parental origin of the alleles inherited by this individual. Computing the probabilities of these transmission events is essential to perform QTL detection methods. Results: A fast algorithm for the estimation of these probabilities conditional to parental phases has been developed. It is adapted to classical QTL detection designs applied to outbred populations, in particular to designs composed of half and/or full sib families. It assumes the absence of interference. Conclusion: The theory is fully developed and an example is given.

引用

页数：9

共 11 条

[1] Alternative models for QTL detection in livestock. I. General introduction [J].