Crystal structure of a NIR-Emitting DNA-Stabilized Ag16 Nanocluster

被引：114

作者：

Cerretani, Cecilia ^{[1
,2
]}

Kanazawa, Hiroki ^{[3
,4
]}

Vosch, Tom ^{[1
,2
]}

Kondo, Jiro ^{[3
]}

机构：

[1] Univ Copenhagen, Dept Chem, Univ Pk 5, DK-2100 Copenhagen, Denmark

[2] Univ Copenhagen, NanoSci Ctr, Univ Pk 5, DK-2100 Copenhagen, Denmark

[3] Sophia Univ, Dept Mat & Life Sci, Chiyoda Ku, 7-1 Kioi Cho, Tokyo 1028554, Japan

[4] Univ Strasbourg, IBMC CNRS, 2 Allee Konrad Roentgen, F-67084 Strasbourg, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2019年 / 58卷 / 48期

关键词：

crystal structure; DNA; fluorescence; self-assembly; silver nanocluster; FLUORESCENT SILVER NANOCLUSTERS; EXCITED-STATE RELAXATION; NUMBERS; CLUSTER; ATOM;

D O I：

10.1002/anie.201906766

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

DNA has been used as a scaffold to stabilize small, atomically monodisperse silver nanoclusters, which have attracted attention due to their intriguing photophysical properties. Herein, we describe the X-ray crystal structure of a DNA-encapsulated, near-infrared emitting Ag-16 nanocluster (DNA-Ag16NC). The asymmetric unit of the crystal contains two DNA-Ag16NCs and the crystal packing between the DNA-Ag16NCs is promoted by several interactions, such as two silver-mediated base pairs between 3 '-terminal adenines, two phosphate-Ca2+-phosphate interactions, and pi-stacking between two neighboring thymines. Each Ag16NC is confined by two DNA decamers that take on a horse-shoe-like conformation and is almost fully shielded from the solvent environment. This structural insight will aid in the determination of the structure/photophysical property relationship for this class of emitters and opens up new research opportunities in fluorescence imaging and sensing using noble-metal clusters.

引用

页码：17153 / 17157

页数：5

共 38 条

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