Frequency of silent myocardial ischemia in type 2 diabetic patients and the relation with poor glycemic control

被引：18
作者：
Araz, M [1 ]
Celen, Z
Akdemir, I
Okan, V
机构：
[1] Gaziantep Univ, Fac Med, Dept Internal Med, TR-27070 Gaziantep, Turkey
[2] Gaziantep Univ, Fac Med, Dept Nucl Med, Gaziantep, Turkey
[3] Gaziantep Univ, Fac Med, Dept Cardiol, Gaziantep, Turkey
来源：
ACTA DIABETOLOGICA | 2004年 / 41卷 / 02期
关键词：
silent myocardial ischemia; type 2 diabetes mellitus; HbA(1c); retinopathy;
D O I：
10.1007/s00592-004-0142-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The aim of the study was to investigate the frequency of silent myocardial ischemia in type 2 diabetic patients without any clinical or laboratory findings of myocardial ischemia and to examine the related factors for silent myocardial ischemia. A total of 116 type 2 diabetic patients (82 women) with a disease duration of 5-20 years were included in the study. All patients underwent stress and resting myocardial perfusion single-photon emission computed tomographic (SPECT) study with Tc-99m-MIBI. Coronary angiography was performed in patients with ischemia established at myocardial perfusion SPECT. Ischemia was determined in 18 (15.5%) patients by myocardial perfusion SPECT. Coronary angiography performed in 17 of these patients confirmed coronary stenosis >50% in 11 patients. Thus, the prevalence of silent myocardial ischemia was 9.6%. Significant relations were found between silent myocardial ischemia and male sex, high HbA(1C) level and retinopathy. Type 2 diabetic patients (especially men) with poorly controlled diabetes mellitus or retinopathy should be screened for silent myocardial ischemia.
引用
收藏
页码：38 / 43
页数：6
相关论文
共 40 条
  • [1] [Anonymous], 1997, Am J Cardiol, V79, P134
  • [2] Angiotensin-converting enzyme gene polymorphism and microvascular complications in Turkish type 2 diabetic patients
    Araz, M
    Yilmaz, N
    Güngör, K
    Okan, V
    Kepekci, Y
    Aynacioglu, AS
    [J]. DIABETES RESEARCH AND CLINICAL PRACTICE, 2001, 54 (02) : 95 - 104
  • [3] PREVALENCE OF SILENT-MYOCARDIAL-ISCHEMIA DETECTED BY 24-HOUR AMBULATORY ELECTROCARDIOGRAPHY, AND ITS ASSOCIATION WITH NEW CORONARY EVENTS AT 40-MONTH FOLLOW-UP IN ELDERLY DIABETIC AND NONDIABETIC PATIENTS WITH CORONARY-ARTERY DISEASE
    ARONOW, WS
    MERCANDO, AD
    EPSTEIN, S
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1992, 69 (05) : 555 - 556
  • [4] EXERCISE-INDUCED SILENT ISCHEMIA - AGE, DIABETES-MELLITUS, PREVIOUS MYOCARDIAL-INFARCTION AND PROGNOSIS
    CALLAHAM, PR
    FROELICHER, VF
    KLEIN, J
    RISCH, M
    DUBACH, P
    FRIIS, R
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1989, 14 (05) : 1175 - 1180
  • [5] ASYMPTOMATIC TRANSIENT ST CHANGES DURING AMBULATORY ECG MONITORING IN DIABETIC-PATIENTS
    CHIARIELLO, M
    INDOLFI, C
    COTECCHIA, MR
    SIFOLA, C
    ROMANO, M
    CONDORELLI, M
    [J]. AMERICAN HEART JOURNAL, 1985, 110 (03) : 529 - 534
  • [6] FREQUENCY OF PAINLESS MYOCARDIAL-ISCHEMIA DURING EXERCISE TOLERANCE TESTING IN PATIENTS WITH AND WITHOUT DIABETES-MELLITUS
    CHIPKIN, SR
    FRID, D
    ALPERT, JS
    BAKER, SP
    DALEN, JE
    ARONIN, N
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1987, 59 (01) : 61 - 65
  • [7] CHUNSHENG L, 1993, CHIN MED SCI J, V8, P118
  • [8] SILENT MYOCARDIAL ISCHEMIA
    COHN, PF
    [J]. ANNALS OF INTERNAL MEDICINE, 1988, 109 (04) : 312 - 317
  • [9] Prevalence and prognostic value of perfusion defects detected by stress technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography in asymptomatic patients with, diabetes mellitus and no known coronary artery disease
    De Lorenzo, A
    Lima, RSL
    Siqueira, AG
    Pantoja, MR
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 2002, 90 (08) : 827 - 832
  • [10] Silent myocardial ischaemia in patients with proved coronary artery disease: a comparison of diabetic and non-diabetic patients
    Ditchburn, CJ
    Hall, JA
    de Belder, M
    Davies, A
    Kelly, W
    Bilous, R
    [J]. POSTGRADUATE MEDICAL JOURNAL, 2001, 77 (908) : 395 - 398
1234