Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis

被引：31
作者：
Wajchenberg, Bernardo Leo [1 ,2 ]
Nery, Marcia [1 ,2 ]
Cunha, Maria Rosaria [1 ,2 ]
Rossi da Silva, Maria Elizabeth [1 ,2 ]
机构：
[1] HC FMUSP, Serv Endocrinol, Sao Paulo, Brazil
[2] HC FMUSP, InsCor, Ctr Diabet Coracao, Sao Paulo, Brazil
来源：
ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA | 2009年 / 53卷 / 02期
关键词：
Obesity; visceral and subcutaneous adipose tissue; low grade inflammation; atherosclerosis; metabolic syndrome; C-REACTIVE PROTEIN; INSULIN-RESISTANCE; OBESE WOMEN; DISEASE; ACTIVATION; STRESS; ORGAN; RISK;
D O I：
10.1590/S0004-27302009000200005
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The authors analyze insulin resistance, the metabolic syndrome and endothelial dysfunction as consequence of a common antecedent, a low grade inflammation, indicating that in obesity there is a chronically activated inflammatory state of the adipose tissue. Furthermore, the inflammatory signaling is discussed according to the adipose tissue depot, visceral or subcutaneous. Arq Bras Endocrino: Metab. 2009;53(2):145-150.
引用
收藏
页码：145 / 150
页数：6
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