Synthesis of Chitosan-Hydroxyapatite Composites and Its Effect on the Properties of Bioglass Bone Cement

被引：0

作者：

Liu, Jingxiao ^{[1
]}

Shi, Fei ^{[1
]}

Yu, Ling ^{[1
]}

Niu, Liting ^{[1
]}

Gao, Shanshan ^{[1
]}

机构：

[1] Dalian Polytech Univ, Sch Chem Engn & Mat, Dalian 116034, Peoples R China

来源：

JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY | 2009年 / 25卷 / 04期

关键词：

Hydroxyapatite; Chitosan; Composites; Bone cement; DRUG-RELEASE; NANOCOMPOSITES; SCAFFOLDS; MICROSPHERES;

D O I：

暂无

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Chitosan-hydroxyapatite (CS-HA) composite powders were synthesized via in situ co-precipitation method, through the reaction of Ca(NO(3))(2) and H(3)PO(4) in the simulated body fluid (SBF) containing appropriate amount of chitosan. The thermal evolution, microstructure and morphology were studied by TG-DTA (thermogravimetry-differential thermal analysis), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy) and TEM (transmission electron microscopy). The in vitro bioactivity test showed that the obtained CS-HA composites had higher capability of inducing calcium ions deposition. Effects of CS-HA composites on the bioactivity and compressive strength of bioglass bone cement were investigated. The results indicated that the bioactivity of bioglass bone cement could be improved further when CS-HA composite powders were added into the cement, and appropriate amount of CS-HA additive was favorable for compressive strength improvement of bioglass bone cement.

引用

页码：551 / 555

页数：5

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