Persistent aplasia after chemotherapy for acute myeloid leukaemia treated with stem cell transplantation from a matched unrelated donor after dose-reduced conditioning

被引：2

作者：

Hambach, L ^{[1
]}

Heil, G ^{[1
]}

Hertenstein, B ^{[1
]}

Ganser, A ^{[1
]}

机构：

[1] Hannover Med Sch, Dept Haematol & Oncol, Hannover, Germany

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2002年 / 118卷 / 02期

关键词：

persistent aplasia; AML; dose-reduced condition-ing; allogeneic peripheral stem cell transplantation; matched unrelated donor;

D O I：

10.1046/j.1365-2141.2002.03742.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Persistent aplasia is a rare complication with poor prognosis after intensive chemotherapy for acute leukaemia. A 59-year-old man with acute myeloid leukaemia (AML), was treated after 186 d of chemotherapy-induced persistent aplasia with an allogeneic peripheral blood stem cell transplantation (PBSCT) from a matched unrelated donor (MUD) after dose-reduced conditioning. The patient remains in complete haematological remission more than 8.5 months after haematological recovery. We believe that this is the first reported case of treatment for chemotherapy-induced persistent aplasia with MUD-PBSCT after dose-reduced conditioning, a procedure that can be successfully performed even in elderly patients.

引用

页码：442 / 444

页数：3

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