Chemical constituents and their antibacterial and antifungal activity from the Egyptian herbal medicine Chiliadenus montanus

被引：24

作者：

Hegazy, Mohamed-Elamir F. ^{[1
,2
]}

Matsuda, Hisashi ^{[3
]}

Nakamura, Seikou ^{[3
]}

Hussein, Taha A. ^{[4
]}

Yoshikawa, Masayuki ^{[3
]}

Pare, Paul W. ^{[5
]}

机构：

[1] Natl Res Ctr, Chem Med Plants Dept, Giza 12622, Egypt

[2] Natl Res Ctr, Ctr Excellence Adv Sci, Giza 12622, Egypt

[3] Kyoto Pharmaceut Univ, Yamashina Ku, Kyoto 6078412, Japan

[4] Delta Univ Sci & Technol, Dept Pharmacognosy, Fac Pharm, Gamasa, Egypt

[5] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA

来源：

PHYTOCHEMISTRY | 2014年 / 103卷

基金：

日本学术振兴会;

关键词：

Chiliadenus montanus; Asteraceae; Dioxane; Sesquiterpenes; Flavonoids; Antimicrobial activity; JASONIA-MONTANA; MARINE SPONGE; SESQUITERPENE; DERIVATIVES; GLYCOSIDES; EXTRACTS;

D O I：

10.1016/j.phytochem.2014.03.027

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Phytochemical investigations of the CH2C12/MeOH (1:1) extract of air-dried aerial parts of Chiliadenus montanus afforded eight metabolites, in addition to eight other previously reported compounds, of which two were isolated for the first time as free acids. Structures were established by spectroscopic methods, including HREIMS, H-1, C-13, DEPT, H-1-H-1 COSY, HMQC and HMBC NMR analysis. Antimicrobial activity against an array of common bacterial and fungal strains was measured via a colorimetric assay with minimal growth inhibition observed in the mu g/mL range for one of the tested metabolites. (c) 2014 Elsevier Ltd. All rights reserved.

引用

页码：154 / 161

页数：8

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