Magnetic resonance spectroscopy: principles and applications in neurosurgery

被引：10

作者：

McLean, Mary A. ^{[1
,2
]}

Cross, Justin J. ^{[1
]}

机构：

[1] Addenbrookes Hosp, Dept Radiol, Cambridge CB2 0QQ, England

[2] Li Ka Shing Ctr, Canc Res UK Cambridge Res Inst, Cambridge, England

来源：

BRITISH JOURNAL OF NEUROSURGERY | 2009年 / 23卷 / 01期

关键词：

Magnetic resonance spectroscopy; tumor; epilepsy; traumatic brain injury; N-acetyl aspartate; choline; creatine; myo-inositol; lactate; TEMPORAL-LOBE EPILEPSY; PROTON MR SPECTROSCOPY; HIGH-GRADE GLIOMAS; HUMAN-BRAIN; IN-VIVO; MULTIPLE-SCLEROSIS; WHITE-MATTER; METABOLIC PROFILES; MALIGNANT GLIOMAS; TUMORS;

D O I：

10.1080/02688690802491673

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Although MRI is a routine and invaluable tool in diagnosis and presurgical planning, the related technique of magnetic resonance spectroscopy (MRS) is not often applied. MRS shows the chemical content of brain tissue and can therefore increase the specificity of diagnosis considerably. It also is able to detect abnormality in some tissues which appear normal on conventional MRI, with potential to aid in both discriminating lesion borders and in predicting post-operative outcome. The physical principles of MRS and its technical limitations are discussed, with examples of applications in tumors, epilepsy and traumatic brain injury.

引用

页码：5 / 13

页数：9

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