Masculinity/Femininity Predicts Brain Volumes in Normal Healthy Children

被引：14

作者：

Belfi, Amy M. ^{[1
,2
]}

Conrad, Amy L. ^{[3
]}

Dawson, Jeffrey ^{[4
]}

Nopoulos, Peg ^{[1
,2
,3
,5
]}

机构：

[1] Univ Iowa, Interdisciplinary Grad Program Neurosci, Iowa City, IA USA

[2] Univ Iowa, Dept Neurol, Carver Coll Med, Iowa City, IA 52242 USA

[3] Univ Iowa, Dept Psychiat, Carver Coll Med, Iowa City, IA 52242 USA

[4] Univ Iowa, Dept Biostat, Iowa City, IA 52242 USA

[5] Univ Iowa, Dept Pediat, Carver Coll Med, Iowa City, IA 52242 USA

来源：

DEVELOPMENTAL NEUROPSYCHOLOGY | 2014年 / 39卷 / 01期

关键词：

SEXUAL-DIMORPHISM; STRUCTURAL MRI; CHILDHOOD; GENDER; ADOLESCENCE; MATTER; TESTOSTERONE; POPULATION; ANDROGYNY; IDENTITY;

D O I：

10.1080/87565641.2013.839681

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Previous research has shown sex differences in brain morphology (De Bellis et al., 2001). However, these studies have not taken gender into account. Gender is a phenotype that describes behavior. In this study, we examined the relationship between gender, sex, and brain volumes in children. One hundred and eight children ages 7 to 17 were administered the Children's Sex Role Inventory (Boldizar, 1991) and obtained volumetric brain data via magnetic resonance imaging (MRI). We found that, in the frontal lobe, higher masculinity predicted greater volumes of white matter. Also, in the temporal lobe, higher femininity predicted greater volumes of gray matter.

引用

页码：25 / 36

页数：12

共 31 条

[1] Automatic atlas-based volume estimation of human brain regions from MR images [J].

Andreasen, NC ;

Rajarethinam, R ;

Cizadlo, T ;

Arndt, S ;

Swayze, VW ;

Flashman, LA ;

OLeary, DS ;

Ehrhardt, JC ;

Yuh, WTC .

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1996, 20 (01) :98-106

[2] Fetal Testosterone Predicts Sexually Differentiated Childhood Behavior in Girls and in Boys [J].

Auyeung, Bonnie ;

Baron-Cohen, Simon ;

Ashwin, Emma ;

Knickmeyer, Rebecca ;

Taylor, Kevin ;

Hackett, Gerald ;

Hines, Melissa .

PSYCHOLOGICAL SCIENCE, 2009, 20 (02) :144-148

[3] Total and Regional Brain Volumes in a Population-Based Normative Sample from 4 to 18 Years: The NIH MRI Study of Normal Brain Development [J].

Ball, William S. ;

Byars, Anna Weber ;

Schapiro, Mark ;

Bommer, Wendy ;

Carr, April ;

German, April ;

Dunn, Scott ;

Rivkin, Michael J. ;

Waber, Deborah ;

Mulkern, Robert ;

Vajapeyam, Sridhar ;

Chiverton, Abigail ;

Davis, Peter ;

Koo, Julie ;

Marmor, Jacki ;

Mrakotsky, Christine ;

Robertson, Richard ;

McAnulty, Gloria ;

Brandt, Michael E. ;

Fletcher, Jack M. ;

Kramer, Larry A. ;

Yang, Grace ;

McCormack, Cara ;

Hebert, Kathleen M. ;

Volero, Hilda ;

Botteron, Kelly ;

McKinstry, Robert C. ;

Warren, William ;

Nishino, Tomoyuki ;

Almli, C. Robert ;

Todd, Richard ;

Constantino, John ;

McCracken, James T. ;

Levitt, Jennifer ;

Alger, Jeffrey ;

O'Neill, Joseph ;

Toga, Arthur ;

Asarnow, Robert ;

Fadale, David ;

Heinichen, Laura ;

Ireland, Cedric ;

Wang, Dah-Jyuu ;

Moss, Edward ;

Zimmerman, Robert A. ;

Bintliff, Brooke ;

Bradford, Ruth ;

Newman, Janice ;

Evans, Alan C. ;

Arnaoutelis, Rozalia ;

Pike, G. Bruce .

CEREBRAL CORTEX, 2012, 22 (01) :1-12

[4] MEASUREMENT OF PSYCHOLOGICAL ANDROGYNY [J].

BEM, SL .

JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1974, 42 (02) :155-162

[5] ASSESSING SEX TYPING AND ANDROGYNY IN CHILDREN - THE CHILDRENS SEX-ROLE INVENTORY [J].

BOLDIZAR, JP .

DEVELOPMENTAL PSYCHOLOGY, 1991, 27 (03) :505-515

[6] Examining the sex difference in lateralisation for processing facial emotion: Does biological sex or psychological gender identity matter? [J].

Bourne, Victoria J. ;

Maxwell, Adele M. .

NEUROPSYCHOLOGIA, 2010, 48 (05) :1289-1294

[7] The human brain age 7-11 years: A volumetric analysis based on magnetic resonance images [J].

Caviness, VS ;

Kennedy, DN ;

Richelme, C ;

Rademacher, J ;

Filipek, PA .

CEREBRAL CORTEX, 1996, 6 (05) :726-736

[8] AUTOMATIC 3D INTERSUBJECT REGISTRATION OF MR VOLUMETRIC DATA IN STANDARDIZED TALAIRACH SPACE [J].

COLLINS, DL ;

NEELIN, P ;

PETERS, TM ;

EVANS, AC .

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1994, 18 (02) :192-205

[9] Sex differences in brain maturation during childhood and adolescence [J].

De Bellis, MD ;

Keshavan, MS ;

Beers, SR ;

Hall, J ;

Frustaci, K ;

Masalehdan, A ;

Noll, J ;

Boring, AM .

CEREBRAL CORTEX, 2001, 11 (06) :552-557

[10] YOUNG-ADULT HUMAN BRAIN - AN MRI-BASED MORPHOMETRIC ANALYSIS [J].

FILIPEK, PA ;

RICHELME, C ;

KENNEDY, DN ;

CAVINESS, VS .

CEREBRAL CORTEX, 1994, 4 (04) :344-360

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