Pyrethroid exposure of the general population - is this due to diet?

被引：103

作者：

Schettgen, T

Heudorf, U

Drexler, H

Angerer, E

机构：

[1] Univ Erlangen Nurnberg, Inst Outpatient, Clin Occupat Social & Environm Med, D-91054 Erlangen, Germany

[2] Dept Publ Hlth, D-60311 Frankfurt, Germany

来源：

TOXICOLOGY LETTERS | 2002年 / 134卷 / 1-3期

关键词：

pyrethroids; urine; biological monitoring; pesticides; general population;

D O I：

10.1016/S0378-4274(02)00183-2

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

Inhabitants (1177) of a residential area in Frankfurt/Main have been investigated with respect to their internal exposure to pyrethroids. Biological monitoring revealed a body burden of pyrethroids. The 95th percentile for the urinary metabolites of pyrethroids, such as permethrin and cypermethrin, cis and trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid (cis-DCCA and trans-DCCA), was determined to be 0.5 and 1.4 mug/l, respectively. 95th percentile for cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid (DBCA), a specific metabolite of deltamethrin, and 4-fluoro-3-phenoxybenzoic acid (F-PBA), a metabolite of cyfluthrin, were 0.3 and 0.27 mug/l, respectively. The metabolic pattern found for these samples points out that pyrethroids are probably ingested orally with daily diet. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：141 / 145

页数：5

共 10 条

[1] Determination of metabolites of pyrethroids in human urine using solid-phase extraction and gas chromatography mass spectrometry [J].