Tinea capitis in early infancy treated with itraconazole: a pilot study

被引：18

作者：

Binder, B. ^{[1
]}

Richtig, E. ^{[1
]}

Weger, W. ^{[1
]}

Ginter-Hanselmayer, G. ^{[1
]}

机构：

[1] Med Univ Graz, Dept Dermatol, Graz, Austria

来源：

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | 2009年 / 23卷 / 10期

关键词：

early infancy; itraconazole; tinea capitis; MICROSPORUM-CANIS; TERBINAFINE; TRICHOPHYTON; EFFICACY; CHILDREN; SAFETY;

D O I：

10.1111/j.1468-3083.2009.03271.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background Tinea capitis is the most common fungal infection of the scalp in childhood, but a very rare disorder in the first year of life. Objective To evaluate the efficacy, tolerability and safety of itraconazole in 7 children aged between 3 and 46 weeks (median: 36 weeks) suffering from tinea capitis caused by Microsporum canis. Methods Prospective case note study. In all patients KOH testing and fungal cultivation on Sabouraud dextrose agar were performed. Results 7 patients (5 girls and 2 boys) were included in the period between 2001 and 2008. The causative etiologic agent was Microsporum canis in all children. The patients received itraconazole 5mg/kg bodyweight daily for 3 to 6 weeks with no clinically side effects being noted. In all patients clinical and mycological cure could be achieved. Conclusion Itraconazole proved to be a safe and effective treatment option for Microsporum canis induced tinea capitis in children in their first year of life.

引用

页码：1161 / 1163

页数：3