Laparoscopic Donor Nephrectomy: A Plea for the Right-Sided Approach

被引:55
作者
Dols, Leonienke F. C. [1 ]
Kok, Niels F. M. [1 ]
Alwayn, Ian P. J. [1 ,2 ]
Tran, T. C. Khe [1 ]
Weimar, Willem [3 ]
Ilzermans, Jan N. M. [1 ]
机构
[1] Erasmus MC, Dept Surg, NL-3000 CA Rotterdam, Netherlands
[2] Dalhousie Univ, Dept Surg, Halifax, NS B3H 4H2, Canada
[3] Erasmus MC, Dept Internal Med, NL-3000 CA Rotterdam, Netherlands
关键词
Laparoscopic donor nephrectomy; Living donors; Kidney transplantation; RANDOMIZED CONTROLLED-TRIAL; RIGHT KIDNEY; LIVE; COMPLICATIONS; EXPERIENCE; RECIPIENT;
D O I
10.1097/TP.0b013e318198a3a6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. Laparoscopic donor nephrectomy (LDN) has become the preferred procedure for live donor nephrectomy. Most transplant surgeons are reluctant toward right-sided LDN (R-LDN) fearing short vessels and renal vein thrombosis. Methods. In our institution, Selection of the appropriate kidney for donation was based on the same criteria that traditionally governed open donor nephrectomy. All intraoperative and postoperative data were prospectively recorded. Results. One hundred Fifty-nine R-LDNs (56%) and 124 left-sided LDNs (L-LDN, 44%) were performed. Demographics did not significantly differ. Complications occurred in 10 (6%) vs. 23 (19%) procedures (R-LDN vs. L-LDN, P=0.002), resulting in 2 and 11 conversions, respectively. Right-sided kidney donation was the only independent preventative factor for complications in multivariate analysis (P=0.008, Odds ratio 0.33). R-LDN was associated with shorter operation time (mean 202 vs. 247 min, P<0.001) and less blood loss (139 vs. 294 mL, P<0.001). Hospital stay was 3 days in both groups. With regard to the recipients, the second warm ischemia time was similar (29 vs. 28 min, P = 0.699). Conclusions. R-LDN is faster and safer than L-LDN and does not adversely affect graft function. R-LDN may be advocated to allow donors to benefit from the advantages of laparoscopic surgery.
引用
收藏
页码:745 / 750
页数:6
相关论文
共 20 条
[1]   Postoperative pain and convalescence in living kidney donors-laparoscopic versus open donor nephrectomy: A randomized study [J].
Andersen, MH ;
Mathisen, L ;
Oyen, O ;
Edwin, B ;
Digernes, R ;
Kvarstein, G ;
Tonnessen, TI ;
Wahl, AK ;
Hanestad, BR ;
Fosse, E .
AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (06) :1438-1443
[2]   Laparoscopic procurement of kidneys with multiple renal arteries is associated with increased ureteral complications in the recipient [J].
Carter, JT ;
Freise, CE ;
McTaggart, RA ;
Mahanty, HD ;
Kang, SM ;
Chan, SH ;
Feng, S ;
Roberts, JP ;
Posselt, AM .
AMERICAN JOURNAL OF TRANSPLANTATION, 2005, 5 (06) :1312-1318
[3]   Fatal and nonfatal hemorrhagic complications of living kidney donation [J].
Friedman, AL ;
Peters, TG ;
Jones, KW ;
Boulware, LE ;
Ratner, LE .
ANNALS OF SURGERY, 2006, 243 (01) :126-130
[4]   Laparoscopic donor nephrectomy: The University of Maryland 6-year experience [J].
Jacobs, SC ;
Cho, E ;
Foster, C ;
Liao, P ;
Bartlett, ST .
JOURNAL OF UROLOGY, 2004, 171 (01) :47-51
[5]   Comparison of right and left laparoscopic live donor nephrectomy [J].
Kay, Mark D. ;
Brook, Nicholas ;
Kaushik, Monika ;
Harper, Simon J. F. ;
Bagul, Atul ;
Nicholson, Michael L. .
BJU INTERNATIONAL, 2006, 98 (04) :843-844
[6]   Proposed classification of complications after live donor nephrectomy [J].
Kocak, B ;
Koffron, AJ ;
Baker, TB ;
Salvalaggio, PRO ;
Kaufman, DB ;
Fryer, JP ;
Abecassis, MM ;
Stuart, FP ;
Leventhal, JR .
UROLOGY, 2006, 67 (05) :927-931
[7]   Donor nephrectomy: Mini-incision muscle-splitting open approach versus laparoscopy [J].
Kok, NFM ;
Alwayn, IPJ ;
Lind, MY ;
Tran, KTC ;
Weimar, W ;
IJzermans, JNM .
TRANSPLANTATION, 2006, 81 (06) :881-887
[8]   The current practice of live donor nephrectomy in Europe [J].
Kok, Niels F. M. ;
Weimar, Willem ;
Alwayn, Ian P. J. ;
IJzermans, Jan N. M. .
TRANSPLANTATION, 2006, 82 (07) :892-897
[9]   Comparison of laparoscopic and mini incision open donor nephrectomy: single blind, randomised controlled clinical trial [J].
Kok, Niels F. M. ;
Lind, May Y. ;
Hansson, Birgitta M. E. ;
Pilzecker, Desiree ;
zur Borg, Irigrid R. A. M. Mertens ;
Knipscheer, Ben C. ;
Hazebroek, Eric J. ;
Dooper, Ine M. ;
Weimar, Willem ;
Hop, Wim C. J. ;
Adang, Eddy M. M. ;
van der Wilt, Gert Jan ;
Bonjer, Hendrik J. ;
van der Vliet, Jordanus A. ;
IJzermans, Jan N. M. .
BRITISH MEDICAL JOURNAL, 2006, 333 (7561) :221-224
[10]   Laparoscopic donor nephrectomy 1997 to 2003: Lessons learned with 500 cases at a single institution [J].
Leventhal, JR ;
Kocak, B ;
Salvalaggio, PRO ;
Koffron, AJ ;
Baker, TB ;
Kaufman, DB ;
Fryer, JP ;
Abecassis, MM ;
Stuart, FP .
SURGERY, 2004, 136 (04) :881-888