Fast electron transfer between glucose oxidase and electrodes via phenothiazine mediators with poly(ethylene oxide) spacers attached to the enzyme surface

被引：22

作者：

Ban, K ^{[1
]}

Ueki, T ^{[1
]}

Tamada, Y ^{[1
]}

Saito, T ^{[1
]}

Imabayashi, S ^{[1
]}

Watanabe, M ^{[1
]}

机构：

[1] Yokohama Natl Univ, Grad Sch Engn, Dept Adv Mat Chem, Hodogaya Ku, Yokohama, Kanagawa 2408501, Japan

来源：

ELECTROCHEMISTRY COMMUNICATIONS | 2001年 / 3卷 / 11期

关键词：

glucose oxidase; phenothiazine; poly(ethylene oxide); bioconjugates; electron transfer;

D O I：

10.1016/S1388-2481(01)00236-3

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

A series of glucose oxidase hybrids capable of a direct electrical communication with electrodes is synthesized by covalently bonding phenothiazine mediators to surface lysine residues via poly(ethylene oxide) spacers with different lengths. The hybrid with the optimum length of spacer chain exhibits the fast electron transfer between the redox center of enzyme and electrodes. This fast electron transfer in the hybrids realizes a large catalytic current comparable to that for the corresponding freely diffusing mediator systems. (C) 2001 Published by Elsevier Science B.V.

引用

页码：649 / 653

页数：5

共 18 条

[1] INTRAMOLECULAR ELECTRON-TRANSFER RATES IN FERROCENE-DERIVATIZED GLUCOSE-OXIDASE [J].