Regioselective alkylation of a methylene group via meta-bridging of calix[4]arenes

被引：8

作者：

Slavik, Petr ^{[1
]}

Dvorakova, Hana ^{[2
]}

Eigner, Vaclav ^{[3
]}

Lhotak, Pavel ^{[1
]}

机构：

[1] Prague Inst Chem Technol, Dept Organ Chem, CR-16628 Prague 6, Czech Republic

[2] ICTP, Lab NMR Spect, Prague, Czech Republic

[3] ICTP, Dept Solid State Chem, Prague, Czech Republic

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 70期

关键词：

SUBSTITUTION; CALIXARENES;

D O I：

10.1039/c4cc04356a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The meta-iodo derivative, fixed in the cone conformation, enables the gram-scale preparation of a meta-bridged calix[4]arene. This intermediate, possessing a fluorene moiety within the macrocyclic skeleton, can be regioselectively alkylated on the corresponding methylene bridge to form a unique substitution pattern in classical calixarene chemistry.

引用

页码：10112 / 10114

页数：3

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