What is the Benefit of Salt Reduction on Blood Pressure? Assessment of the Cochrane Review "Effect of longer-term modest salt reduction on blood pressure. He FJ, Li J, Macgregor GA. Cochrane Database Syst Rev. 2013 Apr 30;4:CD004937.

被引:0
作者
Caldeira, Daniel [1 ]
Vaz-Carneiro, Antonio [2 ,3 ]
Costa, Joao [1 ,2 ,3 ]
机构
[1] Univ Lisbon, Fac Med, Lab Farmacol Clin & Terapeut, P-1699 Lisbon, Portugal
[2] Univ Lisbon, Fac Med, Ctr Estudos Med Baseada, P-1699 Lisbon, Portugal
[3] Ctr Colaborador Portugues Rede Cochrane Iberoamer, Lisbon, Portugal
来源
ACTA MEDICA PORTUGUESA | 2013年 / 26卷 / 05期
关键词
Blood Pressure; Cardiovascular Diseases; Diet Sodium-Restricted; Hypertension; Randomized Controlled Trials as Topic; Sodium Chloride; Dietary;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In the present article we evaluate and comment the systematic review from Cochrane Collaboration "Effect of longer-term modest salt reduction on blood pressure. Cochrane Database Syst Rev. 2013 Apr 30;4:CD004937". Clinical Question: What is the impact of long-term (>= 4 weeks) modest salt (sodium chloride) reduction on arterial blood pressure? Conclusions: This systematic review concluded that a moderate reduction in salt intake (mean reduction -4.4 g per day) resulted in statistically significant decreases in blood pressure (BP) that may be helpful in normotensive (-2.42 mmHg systolic BP; -1.00 mmHg diastolic BP) and hypertensive patients (-5.39 mmHg systolic BP; -2.82 mmHg diastolic BP). There were slight increases in physiological plasma renin activity, aldosterone and norepinephrine, without significant changes in lipid profile.
引用
收藏
页码:490 / 492
页数:3
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