Aplastic Anemia in Adolescents and Young Adults

被引：18
作者：
DeZern, Amy E. [1 ]
Guinan, Eva C. [2 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD USA
[2] Harvard Univ, Sch Med, Boston, MA USA
来源：
ACTA HAEMATOLOGICA | 2014年 / 132卷 / 3-4期
关键词：
Aplastic anemia; Bone marrow failure; Adolescent; Hematopoietic cell transplant; Immunosuppressive therapy; STEM-CELL TRANSPLANTATION; GRANULOCYTE-STIMULATING FACTOR; HIGH-DOSE CYCLOPHOSPHAMIDE; TERM-FOLLOW-UP; IMMUNOSUPPRESSIVE THERAPY; BONE-MARROW; FUNGAL-INFECTION; EUROPEAN GROUP; SIBLING DONOR; BLOOD;
D O I：
10.1159/000360209
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Adolescent and young adult patient presentations of aplastic anemia require a particular perspective on both diagnosis and treatment. This unique age group necessitates a thorough diagnostic evaluation to ensure the etiology, acquired or inherited, is sufficiently determined. The treatment options include human leukocyte antigen-identical sibling hematopoietic cell transplantation or immunosuppressive therapy, and both require attention to the specific medical and social needs of these adolescents and young adults. Longitudinal surveillance throughout life for the development of late complications of the disease and treatment is mandatory. (C) 2014 S. Karger AG, Basel
引用
收藏
页码：331 / 339
页数：9
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