Small molecule enhancers for mutant enzymes in lysosomal disorders

被引:0
作者
Lukas, Jan [1 ]
Pockrandt, Anne-Marie [1 ]
Seemann, Susanne [1 ]
Runge, Franziska [1 ]
Zheng, Chaonan [1 ]
Sharif, Muhammad [2 ]
Pews-Davtyan, Anahit [2 ]
Beller, Matthias [2 ]
Saviouk, Viatcheslav [3 ]
Giese, Anne-Katrin [1 ]
Rolfs, Arndt [1 ]
机构
[1] Univ Rostock, D-18055 Rostock, Germany
[2] Leibniz Inst Catalysis, Rostock, Germany
[3] Centogene GmbH, Rostock, Germany
关键词
D O I
10.1016/j.ymgme.2013.12.166
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
154
引用
收藏
页码:S73 / S73
页数:1
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[41]   LYSOSOMAL ENZYMES IN LEUKEMIA [J].
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