A Case of Granulomatosis with Polyangiitis (Wegener's Granulomatosis) Presenting with Rapidly Progressive Glomerulonephritis

被引：5

作者：

Hasan, Md Rockyb ^{[1
]}

Sakibuzzaman, Md ^{[2
]}

Tabassum, Tahsin ^{[3
]}

Moosa, Sycd Ahmad ^{[4
]}

机构：

[1] Dhaka Med Coll, Internal Med, Dhaka, Bangladesh

[2] Sir Salimullah Med Coll, Internal Med, Dhaka, Bangladesh

[3] Bangabandhu Sheikh Mujib Med Univ, Virol, Dhaka, Bangladesh

[4] Woodhaven Med Profess Corp, Family Med, Queens Village, NY USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2019年 / 11卷 / 10期

关键词：

rapidly progressive glomerulonephritis; necrotizing granulomatous inflammation; lung parenchymal disease; COTRIMOXAZOLE; PREVENTION; VASCULITIS; RELAPSES;

D O I：

10.7759/cureus.5896

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Granulomatosis with polyangiitis (GPA, Wegener's granulomatosis) presenting as rapidly progressive glomerulonephritis is not uncommon. The recognition of multisystem disease involving joints, kidney, and lung is critical for diagnosing Wegener's vasculitis. Here, we report a case study of a 52-year-old Bangladeshi man presented with a history of progressively worsening fever, recurrent cough, and hemoptysis. He developed renal failure within a month which was successfully treated with high-dose steroids, cyclophosphamide, and trimethoprim-sulfamethoxazole (TMP-SMX). Rapidly progressive glomerulonephritis can be a fulminant manifestation of GPA, in which case an immediate and aggressive treatment with pulse steroids, high-dose cyclophosphamide and TMP-SMX can be lifesaving.

引用

页数：5

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