OPINION Metabolism, cell growth and the bacterial cell cycle

被引：217

作者：

Wang, Jue D. ^{[1
]}

Levin, Petra A. ^{[2
]}

机构：

[1] Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA

[2] Washington Univ, Dept Biol, St Louis, MO 63130 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2009年 / 7卷 / 11期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

DNA-REPLICATION INITIATION; ESCHERICHIA-COLI K-12; CHROMOSOME-REPLICATION; BACILLUS-SUBTILIS; GENE DNAA; FTSZ RING; E; COLI; DIVISION; PROTEIN; SIZE;

D O I：

10.1038/nrmicro2202

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Adaptation to fluctuations in nutrient availability is a fact of life for single-celled organisms in the 'wild'. A decade ago our understanding of how bacteria adjust cell cycle parameters to accommodate changes in nutrient availability stemmed almost entirely from elegant physiological studies completed in the 1960s. In this Opinion article we summarize recent groundbreaking work in this area and discuss potential mechanisms by which nutrient availability and metabolic status are coordinated with cell growth, chromosome replication and cell division.

引用

页码：822 / 827

页数：6

共 70 条

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