Primordial germ cell development in zebrafish

被引：38
|
作者：
Raz, E [1 ]
机构：
[1] Max Planck Inst Biophys Chem, D-37070 Gottingen, Germany
来源：
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2002年 / 13卷 / 06期
关键词：
primordial germ cells; PGC; cell migration; germ plasm; zebrafish;
D O I：
10.1016/S1084952102001027
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In sexually reproducing organisms, primordial germ cells (PGCs) give rise to gametes that are responsible for the development of a new organism in the next generation. These cells follow a characteristic developmental path that is manifested in specialized regulation of basic cell functions and behavior making them an attractive system for studying cell fate specification, differentiation and migration. This review summarizes studies aimed at understanding the development of this cell population in zebrafish and compares these results with those obtained in other model organisms.
引用
收藏
页码：489 / 495
页数：7
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