COVID-19 reinfection: prolonged shedding or true reinfection?

被引:37
作者
Falahi, S. [1 ]
Kenarkoohi, A. [2 ]
机构
[1] Ilam Univ Med Sci, Zoonot Dis Res Ctr, Ilam, Iran
[2] Ilam Univ Med Sci, Dept Microbiol, Fac Med, Ilam, Iran
关键词
COVID-19; positive re-test; prolonged shedding; SARS-CoV-2; true reinfection;
D O I
10.1016/j.nmni.2020.100812
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The SARS-CoV-2 pandemic is underway and millions of people have been infected. A large number of patients with COVID-19 have recovered and been discharged. While a number of recovered patients test positive again or even have a recurrence of clinical symptoms. Some researchers believe that a positive retest is related to the long-term persistence of the virus in the body, although there is some evidence in favor of reinfection. In this study, we focus more on the possible reasons for positive retesting, antibody responses, and review of possible reinfection case reports. (C) 2020 The Author(s). Published by Elsevier Ltd.
引用
收藏
页数:4
相关论文
共 22 条
  • [1] [Anonymous], 2020, J MED VIROL, DOI DOI 10.1002/jmv.26241
  • [2] [Anonymous], 2020, CLIN INFECT DIS, DOI DOI 10.1093/cid/ciaa149
  • [3] Bao L, 2020, bioRxiv, DOI 10.1101/2020.03.13.990226
  • [4] SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis
    Cevik, Muge
    Tate, Matthew
    Lloyd, Ollie
    Maraolo, Alberto Enrico
    Schafers, Jenna
    Ho, Antonia
    [J]. LANCET MICROBE, 2021, 2 (01): : E13 - E22
  • [5] Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19
    Chen, Xiangyu
    Pan, Zhiwei
    Yue, Shuai
    Yu, Fei
    Zhang, Junsong
    Yang, Yang
    Li, Ren
    Liu, Bingfeng
    Yang, Xiaofan
    Gao, Leiqiong
    Li, Zhirong
    Lin, Yao
    Huang, Qizhao
    Xu, Lifan
    Tang, Jianfang
    Hu, Li
    Zhao, Jing
    Liu, Pinghuang
    Zhang, Guozhong
    Chen, Yaokai
    Deng, Kai
    Ye, Lilin
    [J]. SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 5 (01)
  • [6] European Centre for Disease Prevention and Control, 2020, REINF SARS COV CONS
  • [7] Goldman Jason D, 2020, medRxiv, DOI 10.1101/2020.09.22.20192443
  • [8] Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound?
    Gousseff, Marie
    Penot, Pauline
    Gallay, Laure
    Batisse, Dominique
    Benech, Nicolas
    Bouiller, Kevin
    Collarino, Rocco
    Conrad, Anne
    Slama, Dorsaf
    Joseph, Cedric
    Lemaignen, Adrien
    Lescure, Francois-Xavier
    Levy, Bruno
    Mahevas, Matthieu
    Pozzetto, Bruno
    Vignier, Nicolas
    Wyplosz, Benjamin
    Salmon, Dominique
    Goehringer, Francois
    Botelho-Nevers, Elisabeth
    [J]. JOURNAL OF INFECTION, 2020, 81 (05) : 821 - 825
  • [9] Asymptomatic Reinfection in 2 Healthcare Workers From India With Genetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2
    Gupta, Vivek
    Bhoyar, Rahul C.
    Jain, Abhinav
    Srivastava, Saurabh
    Upadhayay, Rashmi
    Imran, Mohamed
    Jolly, Bani
    Divakar, Mohit Kumar
    Sharma, Disha
    Sehgal, Paras
    Ranjan, Gyan
    Gupta, Rakesh
    Scaria, Vinod
    Sivasubbu, Sridhar
    [J]. CLINICAL INFECTIOUS DISEASES, 2021, 73 (09) : E2823 - E2825
  • [10] Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients
    Iyer, Anita S.
    Jones, Forrest K.
    Nodoushani, Ariana
    Kelly, Meagan
    Becker, Margaret
    Slater, Damien
    Mills, Rachel
    Teng, Erica
    Kamruzzaman, Mohammad
    Garcia-Beltran, Wilfredo F.
    Astudillo, Michael
    Yang, Diane
    Miller, Tyler E.
    Oliver, Elizabeth
    Fischinger, Stephanie
    Atyeo, Caroline
    Iafrate, A. John
    Calderwood, Stephen B.
    Lauer, Stephen A.
    Yu, Jingyou
    Li, Zhenfeng
    Feldman, Jared
    Hauser, Blake M.
    Caradonna, Timothy M.
    Branda, John A.
    Turbett, Sarah E.
    Larocque, Regina C.
    Mellon, Guillaume
    Barouch, Dan H.
    Schmidt, Aaron G.
    Azman, Andrew S.
    Alter, Galit
    Ryan, Edward T.
    Harris, Jason B.
    Charles, Richelle C.
    [J]. SCIENCE IMMUNOLOGY, 2020, 5 (52)