Polysaccharides from Turbinaria conoides: Structural features and antioxidant capacity

被引:122
作者
Chattopadhyay, Nabanita [1 ]
Ghosh, Tuhin [1 ]
Sinha, Sharmistha [1 ]
Chattopadhyay, Kausik [1 ]
Karmakar, Paramita [1 ]
Ray, Bimalendu [1 ]
机构
[1] Univ Burdwan, Dept Chem, Nat Prod Lab, Golapbag 713104, W Bengal, India
关键词
Turbinaria conoides; Sargassaceae; Sulphated polysaccharide; Antioxidant potency; SULFATED FUCANS; FERULOYL OLIGOSACCHARIDES; ANTICOAGULANT ACTIVITY; ANTIVIRAL ACTIVITY; BROWN; SEAWEEDS; FRACTIONS; ABILITY; ASSAY; POWER;
D O I
10.1016/j.foodchem.2009.05.069
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Since reactive oxygen species (ROS) are involved in initiating and promoting several diseases such as cancer and cardiovascular events, this study was designed to evaluate the antioxidant activity of sulphated polysaccharides purified from Turbinaria conoides. A fucoidan (AF3), one alginic acid (B) and a neutral glucan (C1F2) were isolated. The glucan is made up of beta-(1 -> 3)-linked glucopyranosyl residues and has a molecular mass of 5 kDa. The alginic acid contains equimolar proportions of guluronic and mannuronic acid residues. The fucoiclan is highly branched and has an average molecular mass of 50 kDa, The in vitro antioxidant capacity of the fractions was studied by ferric reducing antioxidant power (FRAP) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays. The fucoidan (AF3) showed the highest potential followed by the alginate (B) and laminaran (C1F2). Taken together, these findings demonstrate that these polysaccharides could be used as natural antioxidants by the food industry. (C) 2009 Published by Elsevier Ltd
引用
收藏
页码:823 / 829
页数:7
相关论文
共 34 条
[1]   Structure and antiviral activity of sulfated fucans from Stoechospermum marginatum [J].
Adhikari, Utpal ;
Mateii, Cecilia G. ;
Chattopadhyay, Kausik ;
Pujol, Carlos A. ;
Damonte, Elsa B. ;
Ray, Bimalendu .
PHYTOCHEMISTRY, 2006, 67 (22) :2474-2482
[2]   Characterization of a neutral polysaccharide with antioxidant capacity from red wine [J].
Aguirre, M. J. ;
Isaacs, M. ;
Matsuhiro, B. ;
Mendoza, L. ;
Zuniga, E. A. .
CARBOHYDRATE RESEARCH, 2009, 344 (09) :1095-1101
[3]  
Ahmed A.E. L. R., 1978, J. Food Biochem, V1, P361, DOI [10.1016/j., DOI 10.1111/J.1745-4514.1978.TB00193.X]
[4]   The ferric reducing ability of plasma (FRAP) as a measure of ''antioxidant power'': The FRAP assay [J].
Benzie, IFF ;
Strain, JJ .
ANALYTICAL BIOCHEMISTRY, 1996, 239 (01) :70-76
[5]  
BLAKENEY AB, 1985, CARBOHYD RES, V140, P319, DOI 10.1016/0008-6215(85)85132-6
[6]   A SIMPLE AND RAPID PREPARATION OF ALDITOL ACETATES FOR MONOSACCHARIDE ANALYSIS [J].
BLAKENEY, AB ;
HARRIS, PJ ;
HENRY, RJ ;
STONE, BA .
CARBOHYDRATE RESEARCH, 1983, 113 (02) :291-299
[7]   A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds [J].
Cumashi, Albana ;
Ushakova, Natalia A. ;
Preobrazhenskaya, Marina E. ;
D'Incecco, Armida ;
Piccoli, Antonio ;
Totani, Licia ;
Tinari, Nicola ;
Morozevich, Galina E. ;
Berman, Albert E. ;
Bilan, Maria I. ;
Usov, Anatolii I. ;
Ustyuzhanina, Nadezhda E. ;
Grachev, Alexey A. ;
Sanderson, Craig J. ;
Kelly, Maeve ;
Rabinovich, Gabriel A. ;
Iacobelli, Stefano ;
Nifantiev, Nikolay E. .
GLYCOBIOLOGY, 2007, 17 (05) :541-552
[8]   A COLORIMETRIC METHOD FOR THE DETERMINATION OF SUGARS [J].
DUBOIS, M ;
GILLES, K ;
HAMILTON, JK ;
REBERS, PA ;
SMITH, F .
NATURE, 1951, 168 (4265) :167-167
[9]   Focus on antivirally active sulfated polysaccharides: From structure-activity analysis to clinical evaluation [J].
Ghosh, Tuhin ;
Chattopadhyay, Kausik ;
Marschall, Manfred ;
Karmakar, Paramita ;
Mandal, Pinaki ;
Ray, Bimalendu .
GLYCOBIOLOGY, 2009, 19 (01) :2-15