Bacterial interference in the nasopharynx and nasal cavity of sinusitis prone and non-sinusitis prone children

The aim of this study was to compare the frequency of recovery of potential pathogens and aerobic: anti anaerobic interfering bacteria in the nasopharynx and nasal cavity of sinusitis Drone (SP) children, with their recovery in non-sinusitis prone (N-SP) children. Nasopharyngeal and nasal cultures were taken from 20 SP and 20 N-SP children. Potential pathogens and aerobic and anaerobic bacteria with interfering capabilities against these micro-organisms were identified. Twenty-one potential pathogens (1.05/patient) were isolated from nasopharyngeal cultures from 14 of the 20 SP children, and 10 (0.5/patient) were recovered from 6 of the 20 NSP (p < 0.05). Bacterial interferencs between two aerobic (alpha and non-haemolytic streptococci) and two anaerobic species (prevotella and peptostreptococcus species) and four potential pathogens was observed. Bacterial interference was noted in 64 instances against 4 potential pathogens by 24 normal flora isolates thai were recovered from 7 of the SP group and in 144 instances by 47 isolates from 18 of the NSP group (p < 0.05). Nineteen potential pathogens (0.9/patient) were isolated from nasal cultures of 13 of the 20 SP children and 8 (0.4/patient) were recovered from 5 of the 20 NSP (p < 0.05). Bacterial interference by similar micro-organisms was noted in 21 instances by 9 normal flora isolates that were recovered from 5 of the SP group, and in 63 instances by 26 isolates from 15 of the NSP group (p < 0.05). Our findings illustrate fur the first time that the nasopharyngeal and nasal flora of NSP children contains more aerobic and anaerobic micro-organisms with interfering capability and less potential pathogens than that of SP children.