Chronic Endometritis: Potential Cause of Infertility and Obstetric and Neonatal Complications

被引:132
作者
Kitaya, Kotaro [1 ,2 ]
Matsubayashi, Hidehiko [1 ]
Yamaguchi, Kohei [1 ]
Nishiyama, Rie [1 ]
Takaya, Yukiko [1 ]
Ishikawa, Tomomoto [1 ]
Yasuo, Tadahiro [3 ]
Yamada, Hisao [2 ]
机构
[1] Reprod Clin Osaka, Kita Ku, Osaka, Japan
[2] Kansai Med Univ, Dept Anat & Cell Sci, Osaka, Japan
[3] Kyoto Prefectural Univ Med, Dept Obstet & Gynecol, Kamigyo Ku, Kyoto, Japan
关键词
CD138; chronic endometritis; endometrial stromal plasmacytes; infertility; obstetric and neonatal complications; PELVIC-INFLAMMATORY-DISEASE; NATURAL-KILLER-CELLS; IMPLANTATION FAILURE; PREGNANCY OUTCOMES; WOMEN; EXPRESSION; HYSTEROSCOPY; ASSOCIATION; RECRUITMENT; MICROPOLYPS;
D O I
10.1111/aji.12438
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Chronic endometritis (CE) is a local inflammatory disease characterized by unusual plasmacyte infiltration in the endometrial stromal areas. CE has been neglected in gynecologic practice, as it is a less symptomatic benign disease that requires demanding and time-consuming histopathologic examinations for the definite diagnosis. Recent studies, however, suggest the association of CE with infertility and obstetric and neonatal complications. In this review article, we aimed to update the knowledge on epidemiology, etiology, and pathogenesis of CE as well as discuss its clinical management from diagnosis to treatment.
引用
收藏
页码:13 / 22
页数:10
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