Infective Endocarditis: Therapeutic Options and Indications for Surgery

被引:14
作者
Malhotra, Aneil [1 ]
Rayner, Jenny [1 ]
Williams, Timothy M. [2 ]
Prendergast, Bernard [1 ]
机构
[1] John Radcliffe Hosp, Oxford Heart Ctr, Oxford OX3 9DU, England
[2] St Peters Hosp, Chertsey K16 0PZ, Surrey, England
关键词
Infective endocarditis; Surgery; Cardiology; Antibiotics; Valvular disease; Echocardiography; Diagnosis; Treatment; Management; Bacteria; Valve surgery; PROSTHETIC VALVE ENDOCARDITIS; EMBOLIC EVENTS; PERIANNULAR COMPLICATIONS; STAPHYLOCOCCUS-AUREUS; ECHOCARDIOGRAPHY; MANAGEMENT; IMPACT; RISK; MORTALITY; DIAGNOSIS;
D O I
10.1007/s11886-014-0464-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Infective endocarditis is a serious, life-threatening condition with mortality of 30 % at one year. Established treatment is a combination of anti-microbial therapy and close interface between multiple specialist teams of cardiologists, microbiologists and cardiac surgeons to ensure availability of early surgery to those patients who require it. There are evidence-based established indications for surgery and a shifting body of evidence advocating earlier surgical intervention. The development of complications is often the driving cause of referral for surgical intervention. Here we discuss the management of infective endocarditis, considering both antimicrobial therapy and indications for surgery to treat this debilitating disease.
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页数:6
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