CO2-triggered release from switchable surfactant impregnated liposomes

被引：3
|
作者：
Hegh, Dylan Y. [1 ]
Mackay, Sean M. [1 ]
Tan, Eng Wui [1 ]
机构：
[1] Univ Otago, Dept Chem, Dunedin 9016, New Zealand
来源：
RSC ADVANCES | 2014年 / 4卷 / 60期
关键词：
CYTOSOLIC DELIVERY; PHOSPHATIDYLETHANOLAMINE LIPOSOMES; LIPID VESICLES; GENE DELIVERY; MACROMOLECULES; DRUG;
D O I：
10.1039/c4ra05387g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Incorporation of an amidine-based switchable surfactant into the lipid membrane of a liposome produces a system that is capable of triggered release upon in situ exposure to CO2. The amount of liposomal contents released is dependent on the concentration of switchable surfactant incorporated. A mechanism of the release is proposed.
引用
收藏
页码：31771 / 31774
页数：4
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