Fluorescent hydrophobic probes based on intramolecular charge transfer state for sensitive protein detection in solution

被引：14
|
作者：
Jun, H
Hong, SY
Yoon, SS [1 ]
Kang, C
Suh, M
机构：
[1] Sungkyunkwan Univ, Dept Chem, Suwon 440746, South Korea
[2] Kyung Hee Univ, Dept Neurosci, Grad Sch E W Med Sch, Yongin 449701, South Korea
来源：
CHEMISTRY LETTERS | 2004年 / 33卷 / 06期
关键词：
D O I：
10.1246/cl.2004.690
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
New hydrophobic intramolecular charge transfer probes, comprising an aminostyryl and a cyanopyranyl moieties, were developed for sensitive protein quantification in solution. The probes exhibited dramatic increase of fluorescence quantum yields with accompanying blue-shift of the emission when bound to protein-sodium dodecyl sulfate (SDS) complexes. Using this emission enhancement, the synthesized probes were successfully applied for determining protein concentrations in solution.
引用
收藏
页码：690 / 691
页数：2
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