Porphyrins and phthalocyanines: promising molecules for light-triggered antibacterial nanoparticles

被引：52
作者：
Mondal, Dhananjoy [1 ]
Bera, Smritilekha [1 ]
机构：
[1] Cent Univ Gujarat, Sch Chem Sci, Gandhinagar 382030, India
来源：
ADVANCES IN NATURAL SCIENCES-NANOSCIENCE AND NANOTECHNOLOGY | 2014年 / 5卷 / 03期
关键词：
photosensitizer; porphyrin; phthalocyanine; nanoparticles; antibacterial; PHOTODYNAMIC THERAPY; SINGLET-OXYGEN; IN-VIVO; ANTIMICROBIAL PROPERTIES; STAPHYLOCOCCUS-AUREUS; ZINC PHTHALOCYANINE; GOLD NANOPARTICLES; BASIC PRINCIPLES; TOLUIDINE BLUE; PART I;
D O I：
10.1088/2043-6262/5/3/033002
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Light-triggered treatments in the presence of photosensitizer and oxygen molecule are prevalent for a wide variety of diseases. The reactive oxygen species (ROS), which are produced in the vicinity of malignant tissue by the light activated sensitizers, are considered as active agents in the photodynamic therapy (PDT). The higher reactivity of photosensitizers in nano state enhances the profile of pharmacokinetics and therapeutic index of the active molecule. In that direction, this review emphasises the application of porphyrin (Por) and phthalocyanine (PC) as nano photosensitizers in the development of antibacterial nanotherapeutic agents for resistant and non-resistant bacteria.
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页数：14
相关论文
共 127 条
[1]   Photodynamic therapy for the treatment of nonmelanomatous cutaneous malignancies [J].
Allison, RR ;
Mang, TS ;
Wilson, BD .
SEMINARS IN CUTANEOUS MEDICINE AND SURGERY, 1998, 17 (02) :153-163
[2]   THE MAN WHO DARED TO THINK SMALL [J].
APPENZELLER, T .
SCIENCE, 1991, 254 (5036) :1300-1301
[3]   Light-activated nanotube-porphyrin conjugates as effective antiviral agents [J].
Banerjee, Indrani ;
Douaisi, Marc P. ;
Mondal, Dhananjoy ;
Kane, Ravi S. .
NANOTECHNOLOGY, 2012, 23 (10)
[4]   Photoactivated Antimicrobial Activity of Carbon Nanotube-Porphyrin Conjugates [J].
Banerjee, Indrani ;
Mondal, Dhananjoy ;
Martin, Jacob ;
Kane, Ravi S. .
LANGMUIR, 2010, 26 (22) :17369-17374
[5]   Antibacterial activity of tetraaryl-porphyrin photosensitizers: An in vitro study on Gram negative and Gram positive bacteria [J].
Banfi, Stefano ;
Caruso, Enrico ;
Buccafurni, Loredana ;
Battini, Valeria ;
Zazzaron, Sandro ;
Barbieri, Paola ;
Orlandi, Viviana .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2006, 85 (01) :28-38
[6]   Nanoparticles as vehicles for delivery of photodynamic therapy agents [J].
Bechet, Denise ;
Couleaud, Pierre ;
Frochot, Celine ;
Viriot, Marie-Laure ;
Guillemin, Francois ;
Barberi-Heyob, Muriel .
TRENDS IN BIOTECHNOLOGY, 2008, 26 (11) :612-621
[7]  
BERTOLONI G, 1992, MICROBIOS, V71, P33
[8]   PHOTOBACTERICIDAL MATERIALS BASED ON PORPHYRINS AND PHTHALOCYANINES [J].
BONNETT, R ;
BUCKLEY, DG ;
BURROW, T ;
GALIA, ABB ;
SAVILLE, B ;
SONGCA, SP .
JOURNAL OF MATERIALS CHEMISTRY, 1993, 3 (03) :323-324
[9]  
Bonnett R., 1989, CIBA F SYMP, V146, P40
[10]   Epidemiology of methicillin-resistant Staphylococcus aureus [J].
Boucher, Helen W. ;
Corey, G. Ralph .
CLINICAL INFECTIOUS DISEASES, 2008, 46 :S344-S349
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