Nalbuphine in pediatric anesthesia

被引：24

作者：

Schultz-Machata, A. -M. ^{[1
]}

Becke, K. ^{[2
]}

Weiss, M. ^{[3
]}

机构：

[1] Med Univ Wien, Klin Abt Allgemeine Anasthesie & Intens Med, Univ Klin Anasthesie Allgemeine Intens Med & Schm, A-1090 Vienna, Austria

[2] Klin Hallerwiese Cnopfsche Kinderklin, Abt Anasthesie & Intens Med, Nurnberg, Germany

[3] Univ Kinderkliniken, Anasthesieabt, Zurich, Switzerland

来源：

ANAESTHESIST | 2014年 / 63卷 / 02期

关键词：

Anesthesia; Analgesics; opioid; Perioperative care; Pain; Drug administration routes; INDUCED RESPIRATORY DEPRESSION; PATIENT-CONTROLLED ANALGESIA; COMMON BILE-DUCT; POSTOPERATIVE PAIN; REGIONAL ANESTHESIA; AGONIST-ANTAGONIST; SPONTANEOUS MOVEMENTS; INTRAVENOUS MORPHINE; PROPOFOL ANESTHESIA; INTRANASAL FENTANYL;

D O I：

10.1007/s00101-014-2293-z

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Efficient and safe pediatric perioperative pain therapy in the context of a multimodal pain therapy concept requires a slight to moderate opioid analgesic. Nalbuphine is a nearly ideal opioid for this purpose due to its unique pharmacological properties as a mu-receptor antagonist/kappa-receptor agonist and a high safety profile. Nalbuphine is used clinically primarily in postoperative pain therapy administered as a bolus, continuous infusion and patient-controlled analgesia. Furthermore, it is administered in different regimens for pediatric diagnostic and interventional sedation.

引用

页码：135 / 143

页数：9