Thiersinines A and B:: Novel antiinsectan indole diterpenoids from a new fungicolous Penicillium species (NRRL 28147)

被引：64

作者：

Li, C

Gloer, JB ^{[1
]}

Wicklow, DT

Dowd, PF

机构：

[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA

[2] USDA ARS, Natl Ctr Agr Utilizat Res, Mycotoxin Unit, Peoria, IL 61604 USA

[3] USDA ARS, Natl Ctr Agr Utilizat Res, Crop Bioprotect Res Unit, Peoria, IL 61604 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 18期

关键词：

D O I：

10.1021/ol026424a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Two novel antiinsectan indole diterpenoids, thiersinines A (1) and B (2), along with seven known paxilline-type compounds, were isolated from organic extracts of a new Penicillium species (P. thiersii NRRL 28147). The structures of 1 and 2 were determined by analysis of 2D NMR data. Thiersinines A and B possess a unique spirocyclic subunit that is unprecedented in previously known compounds of this class. Both compounds exhibit potent activity against the fall armyworm (Spodoptera frugiperda).

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页码：3095 / 3098

页数：4

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