A two year follow-up study of common virus infections in hemodialysis patients in Taiwan

被引:2
作者
Kao, TW [1 ]
Hsu, WA [1 ]
Chen, HS [1 ]
Chen, WY [1 ]
机构
[1] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei 100, Taiwan
关键词
cytomegalovirus; Epstein-Barr virus; hemodialysis; herpes simplex virus; influenza virus; varicella-zoster virus;
D O I
10.1046/j.1525-1594.2002.07053.x
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The study was designed to determine whether hemodialysis patients in Taiwan had a different antibody response to common virus infections compared to the normal population. Serum samples from 18 hemodialysis patients and 21 healthy volunteers were obtained every 3 months for 2 years. Geometric mean titers (GMTs) of immunoglobulin G (IgG) antibodies to cytomegalovirus (CMV), herpes simplex virus (HSV), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), as well as Type A and Type B influenza viruses (Inf. A, Inf. B) were compared between the patient and the control groups. The prevalence rates and the rates of recurrent infection were similar in both groups. However, the patient group had a higher percentage of persons having persistent EBV and CMV infections (p<0.05) and also higher GMTs of antibodies nearly the whole year round, especially significant in September and December (p<0.05). In patients with hepatitis C, their GMTs of EBV, VZV, Inf. A, and Inf. B were higher than those without (p<0.05).
引用
收藏
页码:879 / 883
页数:5
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