Multicomponent azide-alkyne cycloaddition catalyzed by impregnated bimetallic nickel and copper on magnetite

被引：29
作者：
Perez, Juana M.
Cano, Rafael
Ramon, Diego J. [1 ]
机构：
[1] Univ Alicante, Fac Ciencias, Inst Sintesis Organ, E-03080 Alicante, Spain
来源：
RSC ADVANCES | 2014年 / 4卷 / 46期
关键词：
ONE-POT SYNTHESIS; HUISGEN 3+2 CYCLOADDITION; EFFICIENT HETEROGENEOUS CATALYST; NANO-POWDER MAGNETITE; CLICK CHEMISTRY; TERMINAL ALKYNES; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; 1,3-DIPOLAR CYCLOADDITION; 3-COMPONENT REACTION; RECYCLABLE CATALYST;
D O I：
10.1039/c4ra03149k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new bimetallic catalyst derived from nickel and copper has been used successfully for the first time in the multicomponent reaction of terminal alkynes, sodium azide, and benzyl bromide derivatives. The presence of both metallic species on the surface of magnetite seems to have a positive and synergetic effect. The catalyst loading is the lowest ever published for a catalyst of copper anchored on any type of iron support. The catalyst could be easily removed from the reaction media just by magnetic decantation and it could be reused up to ten times without any negative effect on the initial results.
引用
收藏
页码：23943 / 23951
页数：9
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