Global DNA methylation patterns through an array-based approach in small intestinal neuroendocrine tumors

被引：36

作者：

Verdugo, Alberto Delgado ^{[1
]}

Crona, Joakim ^{[1
]}

Starker, Lee ^{[1
,2
]}

Stalberg, Peter ^{[1
]}

Akerstrom, Goran ^{[1
]}

Westin, Gunnar ^{[1
]}

Hellman, Per ^{[1
]}

Bjorklund, Peyman ^{[1
]}

机构：

[1] Uppsala Univ, Univ Uppsala Hosp, Dept Surg Sci, Uppsala, Sweden

[2] Yale Univ, Dept Surg, New Haven, CT USA

来源：

关键词：

PANCREATIC ENDOCRINE TUMORS; CARCINOID-TUMORS; HYPOMETHYLATION; CANCER; HYPERMETHYLATION; ASSOCIATION; INSTABILITY; PROFILES; GENE; ALU;

D O I：

10.1530/ERC-13-0481

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：L5 / L7

页数：3

共 15 条

[1] CpG island methylation in carcinoid and pancreatic endocrine tumors [J].

Chan, AOO ;

Kim, SG ;

Bedeir, A ;

Issa, JP ;

Hamilton, SR ;

Rashid, A .

ONCOGENE, 2003, 22 (06) :924-934

[2] DNA hypomethylation leads to elevated mutation rates [J].

Chen, RZ ;

Pettersson, U ;

Beard, C ;

Jackson-Grusby, L ;

Jaenisch, R .

NATURE, 1998, 395 (6697) :89-93

[3] Hypermethylation of CpG island loci and hypomethylation of LINE-I and Alu repeats in prostate adenocarcinoma and their relationship to clinicopathological features [J].

Cho, N-Y ;

Kim, B-H ;

Yoo, E. J. ;

Moon, K. C. ;

Cho, Y-M ;

Kim, D. ;

Kang, G. H. .

JOURNAL OF PATHOLOGY, 2007, 211 (03) :269-277

[4] Hypomethylation of LINE-1 and Alu in well-differentiated neuroendocrine tumors (pancreatic endocrine tumors and carcinoid tumors) [J].

Choi, In-Seon ;

Estecio, Marcos R. H. ;

Nagano, Yasuhiko ;

Kim, Do Ha ;

White, Jill A. ;

Yao, James C. ;

Issa, Jean-Pierre J. ;

Rashid, Asif .

MODERN PATHOLOGY, 2007, 20 (07) :802-810

[5] Frequent promoter hypermethylation and transcriptional downregulation of BTG4 gene in gastric cancer [J].

Dong, Wenjie ;

Tu, Shuiping ;

Xie, Jing ;

Sun, Pinghu ;

Wu, Yunlin ;

Wang, Lifu .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 387 (01) :132-138

[6] DNA methylation profiling of human chromosomes 6, 20 and 22 [J].

Eckhardt, Florian ;

Lewin, Joern ;

Cortese, Rene ;

Rakyan, Vardhman K. ;

Attwood, John ;

Burger, Matthias ;

Burton, John ;

Cox, Tony V. ;

Davies, Rob ;

Down, Thomas A. ;

Haefliger, Carolina ;

Horton, Roger ;

Howe, Kevin ;

Jackson, David K. ;

Kunde, Jan ;

Koenig, Christoph ;

Liddle, Jennifer ;

Niblett, David ;

Otto, Thomas ;

Pettett, Roger ;

Seemann, Stefanie ;

Thompson, Christian ;

West, Tony ;

Rogers, Jane ;

Olek, Alex ;

Berlin, Kurt ;

Beck, Stephan .

NATURE GENETICS, 2006, 38 (12) :1378-1385

[7] Chromosomal instability and tumors promoted by DNA hypomethylation [J].

Eden, A ;

Gaudet, F ;

Waghmare, A ;

Jaenisch, R .

SCIENCE, 2003, 300 (5618) :455-455

[8] Global and regional CpG methylation in pheochromocytomas and abdominal paragangliomas:: Association to malignant behavior [J].

Geli, Janos ;

Kiss, Nimrod ;

Karimi, Mohsen ;

Lee, Jia-Jing ;

Backdahl, Martin ;

Ekstrom, Tomas J. ;

Larsson, Catharina .

CLINICAL CANCER RESEARCH, 2008, 14 (09) :2551-2559

[9] Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia [J].

Kanduri, Meena ;

Cahill, Nicola ;

Goransson, Hanna ;

Enstrom, Camilla ;

Ryan, Fergus ;

Isaksson, Anders ;

Rosenquist, Richard .

BLOOD, 2010, 115 (02) :296-305

[10] Comparative genomic hybridization identifies loss of 18q22-qter as an early and specific event in tumorigenesis of midgut carcinoids [J].

Kytölä, S ;

Höög, A ;

Nord, B ;

Cedermark, B ;

Frisk, T ;

Larsson, C ;

Kjellman, M .

AMERICAN JOURNAL OF PATHOLOGY, 2001, 158 (05) :1803-1808

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