Diabetes in African American Youth Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study

被引:133
作者
Mayer-Davis, Elizabeth J. [2 ]
Beyer, Jennifer [3 ]
Bell, Ronny A. [1 ]
Dabelea, Dana [4 ]
D'Agostino, Ralph, Jr. [3 ]
Imperatore, Giuseppina [5 ]
Lawrence, Jean M. [6 ]
Liese, Angela D. [7 ,8 ]
Liu, Lenna [9 ]
Marcovina, Santica [10 ]
Rodriguez, Beatriz [11 ]
机构
[1] Wake Forest Univ, Sch Med, Dept Epidemiol & Prevent, Winston Salem, NC 27109 USA
[2] Univ N Carolina, Dept Nutr, Chapel Hill, NC USA
[3] Wake Forest Univ, Sch Med, Dept Biostat Sci, Winston Salem, NC 27109 USA
[4] Univ Colorado Denver, Dept Prevent Med & Biometr, Denver, CO USA
[5] Ctr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
[6] Kaiser Permanante So Calif, Dept Res & Evaluat, Pasadena, CA USA
[7] Univ S Carolina, Ctr Res Nutr & Hlth Dispar, Columbia, SC 29208 USA
[8] Univ S Carolina, Dept Epidemiol & Biostat, Columbia, SC 29208 USA
[9] Univ Washington, Inst Child Hlth, Seattle, WA 98195 USA
[10] NW Res Lab, Seattle, WA USA
[11] Univ Hawaii Manoa, Pacific Hlth Res Inst, Dept Geriatr Med, Honolulu, HI 96822 USA
关键词
METABOLIC SYNDROME PHENOTYPE; NUTRITION EXAMINATION SURVEY; IMPAIRED GLUCOSE-TOLERANCE; DISEASE RISK-FACTORS; 3RD NATIONAL-HEALTH; ACCELERATOR HYPOTHESIS; GLYCEMIC CONTROL; BLOOD-PRESSURE; CELL FUNCTION; BETA-CELL;
D O I
10.2337/dc09-S203
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE - To report the prevalence and incidence of type I and type 2 diabetes among African American youth and to describe demographic, clinical, and behavioral characteristics. RESEARCH DESIGN AND METHODS - Data from the SEARCH for Diabetes in Youth Study, a population-based, multicenter observational study of youth with clinically diagnosed diabetes aged 0-19 years, were used to estimate the prevalence for calendar year 2001 (692 cases) and incidence based on 748 African American case subjects diagnosed in 2002-2005. Characteristics of these youth were obtained during a research visit for 436 African American youth with type 1 diabetes and 212 African American youth with type 2 diabetes. RESULTS - Among African American youth aged 0-9 years, prevalence (per 1,000) of type I diabetes was 0.57 (95% CI 0.47-0.69) and for those aged 10-19 years 2.04 (1.85-2.26). Among African American youth aged 0-9 years, annual type I diabetes incidence (per 100,000) was 15.7 (13.7-17.9) and for those aged 10-19 years 15.7 (13.8-17.8). A1C was >= 9.5% among 50% of youth with type I diabetes aged >= 15 years. Across age-groups and sex, 44.7% of African American youth with type 1 diabetes were over-weight or obese. Among African American youth aged 10-19 years, prevalence (per 1,000) of type 2 diabetes was 1.06 (0.93-1.22) and annual incidence (per 100,000) was 19.0 (16.9-21.3). About 60% of African American youth with type 2 diabetes had an annual household income of <$25,000. Among those aged >= 15 years, 27.5% had an A1C >= 9.5%, 22.5% had high blood pressure, and, across subgroups of age and sex, >90% were overweight or obese. CONCLUSIONS - Type 1 diabetes presents a serious burden among African American youth aged < 10 years, and African American adolescents are impacted substantially by both type 1 and type 2 diabetes. Diabetes Care 32 (Suppl. 2):S112-S122, 2009
引用
收藏
页码:S112 / S122
页数:11
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