Fabrication of antigen sensors using carbon nanotube field effect transistors

被引:6
|
作者
Tani, Kentaro
Ito, Hiroshi
Ohno, Yutaka
Kishimoto, Shigeru
Okochi, Mina
Honda, Hiroyuki
Mizutani, Takashi
机构
[1] Nagoya Univ, Dept Quantum Engn, Chikusa Ku, Nagoya, Aichi 4648603, Japan
[2] Nagoya Univ, Dept Chem Engn & Biotechnol, Chikusa Ku, Nagoya, Aichi 4648603, Japan
[3] Nagoya Univ, Venture Business Lab, Chikusa Ku, Nagoya, Aichi 4648603, Japan
[4] Nagoya Univ, Inst Adv Res, Chikusa Ku, Nagoya, Aichi 4648603, Japan
[5] Japan Sci & Technol Agcy, PRESTO, Kawaguchi, Saitama 3320012, Japan
关键词
nanotube; FET; biosensor; anti body-antigen binding; label free;
D O I
10.1143/JJAP.45.5481
中图分类号
O59 [应用物理学];
学科分类号
摘要
Antigen sensors using carbon nanotube field effect transistors (CNT-FETs) were fabricated. In order to avoid the problem of exposing source and drain electrodes directly to the phosphate buffered saline (PBS) solution, source and drain electrodes were covered with evaporated SiO film. The immobilization of antibodies on the device surface was confirmed by the observation of fluorescence. Drain current in the sensor device was decreased by the antibody-antigen binding, which suggests a potential use of CNT-FETs as antigen sensors.
引用
收藏
页码:5481 / 5484
页数:4
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