Enzymatic activation of lysine 2,3-aminomutase from Porphyromonas gingivalis

被引：13
作者：
Brazeau, Brian J.
Gort, Steven J.
Jessen, Holly J.
Andrew, Amy J.
Liao, Hans H.
机构：
[1] Cargill Inc, Biotechnol Dev Ctr, Eddyville, IA 52553 USA
[2] Cargill Inc, Biotechnol Dev Ctr, Navarre, MN USA
[3] Univ Wisconsin, Dept Biochem, Madison, WI USA
来源：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2006年 / 72卷 / 09期
关键词：
D O I：
10.1128/AEM.01143-06
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The development of lysine 2,3-aminomutase as a robust biocatalyst hinges on the development of an in vivo activation system to trigger catalysis. This is the first report to show that, in the absence of chemical reductants, lysine 2,3-aminomutase activity is dependent upon the presence of flavodoxin, ferredoxin, or Havodoxin-NADP(+) reductase.
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页码：6402 / 6404
页数：3
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